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Central serous chorioretinopathy (central serous chorioretinopathy, CSC) (referred to as \characterized. First by VonGraefe reported in 1866, will occur mostly young and middle-aged patients, male, unilateral disease was significantly more than the eyes, the disease is self-limiting disease, the general course of 3 to 4 months, easy to relapse, recurrent permanent vision loss, although it blindly, but its working life, causing much inconvenience. Benbingfasheng mental excitement, tension, and mental over-related, but because of the difficulty of Pathologically, the disease etiology and pathogenesis of pulp has been plagued generations of Ophthalmology scholars. In the 1960s, fundus fluorescein angiography for the ocular fundus checking, pulp disease research breakthrough progress, this check can reflect in vivo ocular blood - retina barrier and the change of the outer barrier of the ocular fundus diagnosis, differential diagnosis and guide treatment and prognosis of great help. Objective: To observe the analysis by our clinic fluorescent fundus angiography diagnosis of pulp disease in 109 patients (115 eyes) in patients with clinical features and fundus fluorescein angiography angiography (fundus fluoresce-in angiography, FFA) in dynamic performance analysis the pulp disease summarize clinical features, pathogenesis and treatment. Methods: Records of 109 patients (115 eyes) in pulp the general situation of the patients (including newly diagnosed age, disease duration, education level, prevalence), visual situation, fundus examination results (including the situation of the retina, macula situation, retinal vascular situation) and gender, using the Heidelberg confocal laser scanning system (Heidelberg retina angiography, HRA) to line eyes FFA check patients of the 109 cases in the pulp, recording the FFA characteristics (including the distribution of the leakage point type, contrast the performance of sub-type, leakage point ) for analysis. Results: the pulp disease FFA summarize the performance of four types: (1) the leakage point type (including a dot expanding type, the verrucous or window of spray-type glass membrane-like defects like or retinal pigment dermatitis type); (2 ) RPE detachment; (3) mixed complex type; (4) no leakage point type. In 109 patients (115 eyes) patients in pulp, pulp patient morbidity in women than men (1: 6.27) were male and 94 cases (86.24%) and 5 females (13.76%) of the average sick 39.8 years of age, mostly 31 to 40 years old (46.81%), monocular incidence of 103 cases (94.49%), and eye disease in 6 patients (5.5%). 115 eyes, mean visual acuity of 0.5,27 patients (23.48%) visual acuity less than 0.3. Careful history, about 60% of patients with psychological factors affect illness incident. Leakage on the initial issuance or in patients with acute FFA spray type is more common leakage points mostly single. The longer course ink stains like diffusion is more common. 115 eyes, 29 eyes (25.21%), less than two weeks duration, average visual acuity of 0.5 in 17 eyes (58.62%), mainly emitted type, ink stains in 12 cases (41.38%); course of more than 3 months, five cases (4.35%), mean visual acuity 0.6-based ink stains type 3 eyes (60%). About 10% of the leakage points in the foveal 1mm diameter range, the rest around the macula, macular beam at the top of the nose and nipple common, followed by nasal, temporal and infratemporal. Conclusion: FFA important pathological process in pulp disease and lesion. The lesions are the main factors in the pulp patients with vision loss, clinical prognosis and treatment guidance. Fundus fluorescein angiography can accurately display the location and quantity of pigment epithelial barrier destruction through the eyes FFA, patients of the 109 cases in the pulp, we draw the following conclusions: 1. Leakage distance foveal 1mm diameter within poor eyesight. To leakage in the foveal 2mm diameter range, relatively less impact on vision. The lesion or fluorescein leakage point location away from the foveal more near visual acuity worse. Neuroepithelial out of scope greater the leakage infiltration larger the area, the more close to the center of the macula, the more severe visual impairment. Good or bad time of onset of visual acuity no significant sexual relationship, not the longer onset, the worse the vision; vice versa, the shorter the time of onset, not their vision better. Pulp disease is a general state-related diseases, monocular high incidence, it is one of the local manifestations of systemic disease. CSC recurrence may be due to the further development of occult choroidal lesions impaired the local retinal pigment epithelial function and lead to visually dysfunction; the laser closed leakage point there can promote retinal pigment epithelial repair, but can not prevent recurrence. In the future, systemic therapy might be an effective treatment.
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