Dissertation > Excellent graduate degree dissertation topics show

The Study of the Effects of Isoflavones of Puerarin and Daidzein on Bone Metabolism in Ovariectomized Female Rats

Author: LiuZuo
Tutor: GuZhenXin;JinBangZuo
School: Nanjing Agricultural College
Course: Food Engineering
Keywords: Bone metabolism Plant isoflavones Daidzein Puerarin Ovariectomized Female rats
CLC: R580
Type: Master's thesis
Year: 2008
Downloads: 3
Quote: 0
Read: Download Dissertation


The important factor on bone and calcium metabolization, have been studied in present examination. Thus, female-ovariectomized rats model (OVX)and menopause women clinic model have been chosen to dicuss the effect on bone and calcium while lacking of endogenesis estrogen and the action of outer estrogen(puerarin and daidzein); then further discuss the study of the bone calcium metabolism.the on 3M,6M,9M rats.1 The functionality study between the change of bone and caliumThe 3M,6M, and 9M SD Rats have been set up,6M-OVX and 9M-OVX groups, analyzed the BMC、BMD and the calcium content in the bone. The result indicated that compared with the 6M, the BMC (P<0.01)、BMD(P<0.05) have prominenced decreased in 9M and 6M-OVX, they have no prominenced difference between 9M-OVX and 9M groups.2 The effect of the bone metabolization by puerarin and daidzeinThe OVX(3M, SD Rats) have been set up and given puerarin and daidzein for 3 months and 6months, then mensurated serum Ca, P, and ALP,. The result show that high dosage puerarin and daidzein can increase the serum Ca, can increase the serum ALP (P<0.05, P<0.01) and decrease moreover decrease the serum ALP (P<0.05, P<0.01) in 9M ovariectomized rats.3 The clinic effect of puerarin and daidzein on bone metabolization of menopause womenResearch on the danger public of osteoporosis, gived the puerarin, daidzein and calcium-D for 3 months, determined BMD, serum Ca and ALP. The result showed that BMD has no difference between groups, the group gived puerarin and calcium-D have decreased on serum Ca(P<0.05), the ALP have increased with puerarin and daidzein, the ALP has no change with calcium-D.

Related Dissertations

  1. The Beneficial Effects of Soy Isoflavones in Osteoporosis of Ovariectomized Rats,R580
  2. Research on the Mechanism of Bone Metabolism Disor-ders of Osteonecrosis of Femoral Head,R681.8
  3. Relationship between 25-(OH)D3 and Disease Activity and Bone Metabolism in Ankylosing Spondylitis,R593.23
  4. The Effect of Different Frequency Impulse Electro Magnetism on OPG Gene Knock-out Mice Which Were Suffered from Osteoporosis,R580
  5. The Experimental Study about Protective Effects of Puerarin on Liver of Brain-dead Rats,R285
  6. Therapeutic Effects of BMSCs Combined Puerarin to Treatment Cerebral Ischemia in Rat,R285.5
  7. Zuoguiwan to the Bone of TGF - β1 , Smad4 signal transduction pathway,R285
  8. Dendritic polymer polyamide - the amine - puerarin Composites and its impact on the cornea,R944
  9. Eight kinds of drugs and eight kinds of infusions and puerarin stability of compatibility with the SMI,R942
  10. The Effect and Potential Mechanism of CP and SP on Hepatoma Carcinoma SMMC-7721 Cell,R735.7
  11. Effects of Clenbuterol & Propranolol on Bone Metabolism in Ovariectomized Rats,R580
  12. Research on the Effects of Atorvastation on Glucose Tolerance、Bone Metabolism in Rats and Its Mechanisms,R587.1
  13. Exploration of Salivary Therapeutic Drug Monitioring in TCM Injections,R286
  14. Effects of Different Doses of Puerarin on Proliferation and Migration of Vascular Endothelial Cell from Human Umbilical Cord Blood,R285.6
  15. The Effects and Mechanisms of Benefiting-bone Granule Against Osteoporosis,R285.5
  16. Effects of Calcitonin on Articular Cartilage Degeneration and on Subchondral Bone Metabolism of Osteoarthritic Rabbit Knee in Vivo and in Vitro,R684.3
  17. Preparation, Characterization of PAMAM Dendrimers-coated Liposomes and Evaluation for Ophthalmic Drug Delivery,R283
  18. The Effect of Peurarin Pretreatment on Endothelial Nitric Oxide Synthase in Brain Tissue and Protective Mechanisms of It on Brain in the Early Stage of Cerebral Ischemia in Rat,R285.5
  19. Study on Quality Control and Pharmacokenetics of Xinnaoliantong Capsual,R285
  20. The Effect of Chinese Medicine on Oxygen Free Radicals and Trace Element in Acute Lung Injure,R285

CLC: > Medicine, health > Internal Medicine > Endocrine diseases and metabolic diseases
© 2012 www.DissertationTopic.Net  Mobile