Dissertation > Excellent graduate degree dissertation topics show

Relationship between Level of Serum Uric Acid and Lower Extremity Arterial Disease in Patients with Type 2 Diabetes Mellitus

Author: YeYing
Tutor: LiXianWen
School: Zunyi Medical College,
Course: Internal Medicine
Keywords: Type 2 diabetes mellitus Lower extremity arterial disease Ankle brachial index Serum uric acid
CLC: R587.1
Type: Master's thesis
Year: 2011
Downloads: 4
Quote: 0
Read: Download Dissertation

Abstract


Objective:To explore the relation that level of serum uric acid (SUA) and lower extremity arterial disease (LEAD) in patients with type 2 diabetes mellitus (T2DM), serum uric acid was measured in T2DM patients.Methods:Eigthy-two cases with type 2 diabetes mellitus at Endocrinology Department in our hospital were recruited. Height, weight were measured to calculate Body Mass Index(BMI) and blood pressure was measured; serum uric acid, serum urea, serum creatinine, plasma glucose, glycosylated hemoglobinAlc (HbAlc), connecting peptide, blood lipids, microalbuminuria (MAU) were measured; ankle brachial index(ABI)was used as diagnostic criteria to determine the presence of LEAD. Research objects were divided into two groups by with or without LEAD, LEAD group (27cases) and Non-LEAD group (55 cases). Related clinical indicators and chronic diabetic complications between tow groups were statistically analyzed.Results:(1) Serum uric acid level (426.15±72.75) of LEAD group was obviously higher than that (331.71±68.67) of none LEDA group (P< 0.05). (2) Prevalence rate of HUA in T2DM patients with LEAD was significantly higher than that of none LEAD (P< 0.05). (3) After getting rid of confounding factors, multi-factor logistic stepwise regression analysis showed that serum uric acid was associated with LEAD (P<0.05).Conclusions:With increased serum uric acid level, incidence of LEAD in patients with type 2 diabetes mellitus was higher. Serum uric acid was close related with LEAD, and serum uric acid was independent risk factor for LEAD.

Related Dissertations

  1. Study on Extracting Process of Rhizoma Alismatis and Rhizoma Smilacis Glabrae and Their Hypouricemic Effects,R284
  2. Efficacy and Safety of Biphasic Insulin Aspart 30 Once-daily Treatment in Patients with Type 2 Diabetes,R587.1
  3. The Blood Glucose Control and Influencing Factors in Type 2 Diabetic Patients with Oral Hypoglycemic Agents,R587.1
  4. Association of Genetic Variation of UTS2 Gene with Type2 Diabetes Mellitus and Hypertension,R587.1
  5. Effect of Gastric Bypass on the Blood Glucose Level in Type 2 Diabetes Rat Model,R587.1
  6. Relationship between Postprandial Blood Pressure and Lower Extremity Arterial Disease in Patients with Type 2 Diabetes Mellitus,R587.1
  7. Explore elastosonography carotid artery in patients with essential hypertension and flexibility in the application of radial artery,R544.1
  8. Ankle-brachial index combined ultra- sensitivity C-reactive protein determination of the value of coronary artery disease,R541.4
  9. The Comparison of Therapeutic Effect and Security between CSⅡ and MDI in Type 2 Diabetes Mellitus,R587.1
  10. The Characteristics of Coronary Angiography in Type 2 Diabetes Mellitus Patients with Suspected Coronary Artery Disease,R587.1
  11. Effect of Whey Protein on Improving Insulin Resistance and the Underlying Mechanisms,R587.1
  12. The Changes of T Lymphocyte Subsets and Costimulatory Molecules Before and After Shuxuetong Treatment in Type 2 Diabetes Subjects with Diabetic Kidney Disease,R692
  13. 50 Cases of Type 2 Diabetic Patients Serum Trace Element and Vitamin Change Analysis,R587.1
  14. Correlation Studies of Plasma Fatty Acids and Type 2 Diabetes Mellitus: Case Control Study,R587.1
  15. Risk Factors and Their Interaction of Type 2 Diabetes Mellitus among Rural Residents in Wang Cheng,R587.1
  16. Effects of New Intravenous Infusions on Blood Glucose Variability in Elderly Type 2 Diabetic Patients,R587.1
  17. Clinical Observation on the Efficacy and Safety of Biphasic Insulin Aspart 30 for the Treatment of 234 Patients with Type 2 Diabetic,R587.1
  18. Comparison of Differences in Bone Mineral Density and Its Related Factors for Patients with Type 2 Diabetes Mellitus of Han, Uygur Nationalities in Xinjiang,R587.1
  19. Energy Supply and Nutritional Intervention Study in Hospitalized Patients with Type 2 Diabetes,R587.1
  20. Expression of Chemerin in Liver of Diet Induced Type 2 Diabetic Rats with IL-6 Intervention,R587.1

CLC: > Medicine, health > Internal Medicine > Endocrine diseases and metabolic diseases > Islet disease > Diabetes
© 2012 www.DissertationTopic.Net  Mobile