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Objective: To investigate the pathological basis of hypertension in patients with cerebral hemorrhage, cerebral hemorrhage in the brain tissue around the hematoma. Methods: Chengdu Second People's Hospital of Neurosurgery admitted between November 2009 to August 2010 meet cerebrovascular disease prevention and treatment guidelines and WHO / ISH standard 40 cases of cerebral hemorrhage hypertension patient information, including: medical records and CT results, surgery and histological findings, the prognosis of the case investigation. All information obtained through access to clinical records, telephone and letters. Using statistical methods to deal with the basic data of the data, pathological findings, patients were divided into to find the hyalinosis group and found no hyalinosis group; discovered vasodilation change the group and not change the group to explore hyaline degeneration and vasodilation changed with patients gender, age, hypertension grading, suffering from high blood pressure relationship of time and the amount of bleeding, and not found of hyalinosis group and found no blood vessels to dilate change groups were compared. The use of statistical methods to obtain meaningful results. Results: pathological specimens, we found that there are different degrees of hyalinization in the hematoma surrounding brain tissue, most of the arterioles; part arterioles expansionary change perivascular tissue gliosis, focal necrosis and inflammatory cell infiltration. Hyaline degeneration grouped according to whether biopsy, the patient's age between the groups, the onset time of the amount of bleeding and the risk of high blood pressure, a statistically significant difference; vasodilatory changes grouped according to whether found between the groups of patients age The same amount of bleeding and suffering from high blood pressure incidence of significant statistical difference. Conclusion: The results of this study suggest that hypertensive patients with brain arterioles hyalinosis and vasodilation changes with age, suffering from high blood pressure related to the length of time. Hyaline degeneration and expansionary change in the small blood vessels of the brain of patients with hypertension are somewhat closely related to the amount of bleeding and cerebral hemorrhage. In addition, the study also get some other results, such as the amount of bleeding associated with admission GCS score and six months after the prognosis; Local hypertensive patients cerebral hemorrhage gender, age distribution and bleeding site; hospital neurosurgery in the efficacy of surgical treatment for hypertensive intracerebral hemorrhage.
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