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Development and Evaluation about PRO Scale of Arthritis Disease

Author: BaiWenZuo
Tutor: WangHongQi;ZhangYanBo
School: Shanxi Medical
Course: Social Medicine and Health Management
Keywords: Patient-reported outcome (PRO) Item Response Theory (IRT) Arthritis Scale
CLC: R195
Type: Master's thesis
Year: 2011
Downloads: 70
Quote: 0
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Abstract


Objective: the the PRO scale of production in accordance with the U.S. Food and Drug Administration (FDA) under the principles and processes of the evaluation of the scale to establish the patient feel formulate suitable the arthritis patient health Clinical evaluation of arthritis PRO scale, through a large number of clinical research, revision and assessment of the scale reliability and validity, and its correction, the final form of the final scale, so that it is more widely used in clinical efficacy evaluation. Method: According to the PRO scale formulate norms, combined with arthritis theoretical knowledge, through access to literature and ask the patient form entry pool, correct and delete the entry pool formed by the Expert Group and its language debugging, forming initial scale. Select three hospitals in Taiyuan pre-survey, effective outpatient 178 questionnaires were returned, 144 pairs of coefficient of variation method, project analysis and item response theory, factor analysis, correlation coefficient method valid questionnaires before and after treatment, hospitalization, Cronbach alpha coefficient method, the method of test-retest reliability screening as a full scale of 45 indicators, then the reliability, validity, and responsiveness assessment. Results: arthritis PRO scale consists of four areas, 12 areas and 45 entries. The scale of Cronbach sα coefficient of physiological functions 0.904 psychological function of 0.808, the social function of 0.648 treatment feelings of 0.754, the whole scale of Cronbach, the sα for 0.884. The whole scale split-half reliability coefficient of 0.941 in all areas split-half reliability coefficients were 0.909,0.883,0.851,0.768. Dimension of the relevant terms of the 18 entries in the field of physiological functions, of which there are 15 entries in the correlation coefficient r 0.50; seven entries in the field of mental function, which has five entries in the correlation coefficient r above 0.70 ; social function field of eight entries, including five entries correlation coefficient r 0.50; 12 entries in the field of treatment of feelings, of which there are nine entries in the correlation coefficient r more than 0.50 Scale The correlation coefficient between the score with the total score of each dimension were 0.856,0.710,0.673,0.358. Construct validity, in addition to the field of physiological functions CFI of 0.860, each of the other areas of the CFI are greater than 0.90, the overall model fit. Reaction in terms of, in addition to the surface of the skin symptoms and effort in the field of physiological functions, self-confidence in the field of mental function, social support and social activities in the field of social function as well as the field of social function, observed object no statistical difference before and after treatment significance (P gt; 0.05), the other aspects and areas of statistical significance. Conclusion: arthritis PRO scale has good reliability, validity and responsiveness.

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