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Objective: To evaluate the immunohistochemical markers matter PAX - 5 ( B - cell -specific activator protein , BSAP ) small cell lung cancer . Methods: A retrospective analysis of the Sino-Japanese Friendship Hospital , Jilin University, Department of Respiratory Medicine , the complete thoracic surgery and oncology data from January 2007 to January 2009 were confirmed by pathology and immunohistochemistry confirm the diagnosis of small cell lung cancer 89 cases have been immunohistochemical markers PAX - 5 ( BASP ) staining , age, gender, smoking history, type, degree of differentiation , clinical stage, surgery , chemotherapy, radiotherapy , PS score and Pax -5 ( BASP ) for univariate survival rates estimated with the log-rank test was significant , and multi-factor Cox regression model analysis . The survival time was the time from diagnosis to the time of death or follow-up termination time . Results : This single factor analysis and Cox regression multivariate analysis showed that : PAX - 5 ( BASP ) , type, degree of differentiation , clinical stage , surgery , chemotherapy , radiotherapy , PS scores were associated with small cell lung cancer , radiotherapy chemotherapy and surgical treatment of three different therapy was a protective factor , the relative risk ( risk factors ) RR lt ; reduces the risk of death . PAX - 5 , clinical stage, differentiation and PS of risk factors RR GT ; increased risk of death , so the pax - 5 adverse factors to influence the prognosis of small cell lung cancer .
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