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Non-small Cell Lung Cancer Analysis of 133 Cases of CVATS Lobectomy

Author: WuJunPeng
Tutor: LiJiLiang
School: Dalian Medical University
Course: Surgery
Keywords: Full video-assisted thoracic surgery Non - small cell lung cancer Lobectomy Lymph node dissection
CLC: R734.2
Type: Master's thesis
Year: 2011
Downloads: 5
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Abstract


Objective: To investigate the value of video-assisted thoracoscopic (VATS) in treatment of lobectomy and lymph nodes dissection for primary non-small cell lung cancer by comparing conventional thoracotomy lobectomy with complete lobectomy and lymph nodes dissection by VATS.Methods: A retrospective analysis of 234 data of primary peripheral non-small cell lung cancer patients from February 2006 to February 2011 after complete lobectomy and lymph nodes dissection. Included the control group 101cases by conventional thoracotomy lobectomy and lymph nodes dissection, the experimental group 133 cases by VATS. To compare operation time, blood loss, lymph node dissection, the time of the chest drainage, pleural drainage, postoperative hospital stay time, postoperative pain intensity, complications, prognosis and death.Results: All patients completed lobectomy and systematic lymph node dissection. There were no deaths or serious complications in two groups. In the experimental group, blood loss(132.1±22.5)ml, operation time(180.9±5.1)min, removed lymph nodes 5-10 group. An average of 7.1±0.18 group, which average 5.5 lymph node stations N1, N2 lymph node station on average 8; postoperative pain intensity (2.54±0.12)degrees, postoperative drainage(470.2±0.27)ml, the time of the chest drainage(4.7±0.27)d, perioperative complications in 13 cases, 0 cases of perioperative death; after I,Ⅱ, period,Ⅲa period of 3 years and 5 year survival rates (88.8%, 76.1%); (61.7%, 42.5%); (33.3%, 16.7%). There were no significant difference between two groups in operation time and terms of lymph node dissection (p>0.05). blood loss, postoperative length of time with a tube, postoperative drainage, postoperative hospital stay and postoperative pain intensity were significant statistically difference (p<0.05). Conclusion: The complete thoracoscopic lobectomy with systemic lymph node dissection and conventional thoracotomy lobectomy with lymph nodes There were Less blood loss, less postoperative drainage, patients with tube length, shorter postoperative hospital stay; less postoperative pain, recover faster, less effect on the activities of patients after. Long-term follow-up 3 years, no significant difference in 5-year survival rate. In short,CVATS lobectomy can be done and dissected lymph node systematically, can be a safe, feasible, and more minimally invasive surgery, can be the future direction of development of thoracic surgery.

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