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CT Characteristics and Pathological Correlation of Lung Tumor with Cysts

Author: LiuLin
Tutor: ZhaoShaoHong
School: PLA Postgraduate Medical School
Course: Medical Imaging and Nuclear Medicine
Keywords: Lung cancer Spiral CT Pathology
CLC: R734.2
Type: Master's thesis
Year: 2011
Downloads: 45
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Abstract


Objective: control by the discovery of 25 cases of chest CT scans CT image characteristics and pathological type of lung tumor lesions containing cysts, to raise awareness with such characteristic lesions, as well as explore the pathological basis of the formation of cysts. Methods: A retrospective analysis of the line in the People's Liberation Army General Hospital in January 2008 -2011 in April multidetector CT chest scan showed the the intrapulmonary tumor cases, screening 25 cases containing cysts intrapulmonary tumors confirmed by surgery or biopsy lesions. The clinical data collected and analysis, including age, sex, clinical symptoms, anatomical site, CT findings, clinical stage, pathological type summarize and analyze. Select the 12 cases of biopsy and CT images of contrast, to observe the pathological basis of the formation of cysts. Results: this group of patients a total of 25 cases were male and 14 cases, 11 females. Age 32-75 years, mean age 54 ± 14.5 years, clinical symptoms of 17 cases of the disease found in the physical examination, cough, sputum or sputum with bloodshot six cases, other parts of malignancy in the remaining two cases, there is no apparent respiratory clinical symptoms. 25 cases occurred in five cases of the left upper lobe, left lower lobe four cases, the right upper lobe seven cases, the right middle lobe in 1 case, the right lower lobe eight cases. This group of patients CT findings: The group of lesions are solitary lesion size 1.0cm-7.3cm, appear lobulation in 22 cases (88.0%), spiculation in 17 cases (68.0%), pleural indentation in 19 patients (76.0% ), vascular convergence sign in 19 cases (76.0%), of vacuole sign or air bronchogram in 17 cases (68.0%). The cysts main type in 6 cases, cysts and solid lesions, 19 cases of mixed. Clinical staging: Ⅰ 12 cases (48.0%), including 7 cases of stage Ⅰ A, Ⅰ B 5 cases; Ⅱ 9 patients (36.0%) were stage Ⅱ A; Ⅳ 3 cases (12.0%); precancerous lesions 1 case (4.0%). Adenocarcinoma of 21 cases (84.0%), including: - poorly differentiated adenocarcinoma in 11 cases, pure bronchioloalveolar carcinoma, adenocarcinoma with bronchioloalveolar carcinoma mixed nine cases;, large cell carcinoma in 1 case (4.0%) ; metastases in 2 cases (8.0%), 1 case of transfer of the right breast, the other was left parotid gland adenoid cystic carcinoma metastasis; atypical adenomatous hyperplasia (AAH) 1 (4.0%). Light microscope, visible inside the tumor necrosis formation of cysts, or for the growth of tumors along the alveolar walls and alveolar wall destruction fuse to form cysts. 2 cases with cysts of lung nodules after 6 months follow disappear cysts, nodules consolidation. Conclusion: the lungs of tumor containing cysts, the majority of lung CT image more than the typical signs of peripheral lung cancer, the pathological mechanism of cyst formation is divided into two categories, one for tumor growth along the alveolar wall, alveolar wall destroy the fuse to form containing the airbag chamber, the other inside the tumor necrosis, the thin-walled hollow formed by the bronchioles exclude. Cysts of the lung tumors, especially in peripheral lung cancer, cysts typically represent the early stages of tumor growth, lesions continue to develop, will form a solid nodule or mass of the lungs.

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CLC: > Medicine, health > Oncology > Respiratory system tumors > Lung tumors
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