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Comparative Study of Imaging and Pathology of Intracranial Tumor

Author: WangJiaNing
Tutor: GengZuoJun
School: Hebei Medical University
Course: Medical Imaging and Nuclear Medicine
Keywords: Intracranial tumors Histopathology Age Gender Misdiagnosed CT MRI Primitive neuroectodermal tumors NMR MRI findings Primary central nervous system lymphoma Magnetic resonance imaging Diagnostic Imaging
CLC: R739.4
Type: Master's thesis
Year: 2011
Downloads: 36
Quote: 0
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Abstract


The first part of the statistical analysis of 1179 cases of intracranial tumors Objective: To study the incidence of intracranial tumors law, improve their preoperative diagnosis rate. Methods: age, sex, histopathological type, 2007 to 2009, 1179 cases confirmed by pathology in patients with intracranial tumors were retrospectively analyzed. Reference to the 2007 WHO classification of central nervous system tumors, and the statistical results compared with the literature, to explore the group of 1179 cases of intracranial tumor occurrence regularity. Results: age of onset of the peak of 40 to 60 years old, women slightly more than men, the histopathological type meningeal tumors (30.28%), the neuroepithelial tissue tumors (29.7%), pituitary adenomas (20.78%), schwannoma ( 10.77%), metastases (2.97%), craniopharyngioma (2.37%), lymphoma (1.44%) of chordoma (0.76%), germ cell tumor (0.68%) and others (0.25%). Meningeal tumor neuroepithelial cells in tumor incidence was slightly lower than previous reports the former to the latter with a high incidence. Children group common pathological type astrocytomas (30%), the ependymoma (13.33%), of craniopharyngioma (13.33%) and medulloblastoma (8.33%). The elderly group common pathological type meningioma (31.78%), the astrocytoma tumor (22.03%), pituitary tumors (14.83%) and schwannoma (10.17%). Conclusion: intracranial tumors with a certain regularity in terms of gender, age and histopathological type. In recent years, with the development of imaging technologies, the increase in incidence. The second part of the intracranial tumor CT, MRI misdiagnosis analysis purposes: analysis of intracranial tumors CT, MRI causes of misdiagnosis and improve the rate of correct diagnosis. Methods: Retrospective analysis of pathologically confirmed 56 cases of CT, MRI misdiagnosed cases of imaging findings, summarized the causes of misdiagnosis. Image data of each of the misdiagnosed patients repeatedly observed sum up of the original diagnosis of mistakes, mainly from the following aspects: (1) positioning error; the ② \one-sided misdiagnosed. Results: CT, MRI misdiagnosis rate of 14.7%. These benign tumors in 26 cases, malignancy in 28 cases, 2 cases of benign and malignant junction tumors constitute more than 46.4%, 50%, and 3.6%, respectively. Astrocytic tumors are the most common type of pathological misdiagnosed tumor. The higher rate of misdiagnosis of tumors, lymphoma, primitive neuroectodermal tumor, metastatic tumor, ependymoma, misdiagnosis rate of 71.43%, 60%, 38.46%, and 33.33%, respectively. Positioning error of 27 cases, eight cases of the \Conclusion: To sum up misdiagnosed cases continue to avoid misdiagnosis; confirmed cases have been difficult to narrow the differential diagnosis. The third part of Adult intracranial primitive neuroectodermal tumor MRI for diagnostic purposes: to explore adult intracranial primitive neuroectodermal tumor (PNET) MRI features to improve the rate of preoperative diagnosis of this disease. Methods: A retrospective analysis of the MRI findings in the PNET patients of five cases in our hospital confirmed by surgery and pathology. Results: The tumors were large, round, shallow leaf mass effect. 5 patients, 1 patient had obvious peritumoral edema, patients with mild peritumoral edema, 3 cases of peritumoral edema. The scan showed a slightly longer T1 longer T2 signal, enhanced tumor parenchyma was obvious uniform or irregular ring enhancement, necrosis, cystic and common bleeding, 2 cases of intracranial metastasis, 2 cases of pulmonary metastases. Conclusion: PNET MRI findings have certain characteristics, important value of MRI to determine the diagnosis and treatment of this disease programs. The fourth part of primary central nervous system lymphoma MRI findings Objective: To study the MRI findings of primary central nervous system lymphoma (PCNSL). Methods: A retrospective analysis of the MRI findings of seven cases of PCNSL patients. Results: single lesion in 4 cases, 3 cases of multiple lesions. 11 lesions were located in four frontal lobe, parietal lobe, temporal lobe and cerebellar hemispheres of the two, a corpus callosum. Low or slightly low signal on T1WI, T2WI showed high signal or slightly higher signal, FLAIR hyperintense or slightly higher signal, DWI high signal. The enhanced scanning lesion intense and homogeneous, showing that the \With cystic necrosis 5, two bleeding. 8 light - moderate edema, severe edema 3. Conclusion: MRI findings of primary central nervous system lymphoma have certain characteristics, but more difficult to make the correct diagnosis for atypical cases.

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