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Objective: To study diabetic patients with cerebral infarction and MRI features of the clinical features, aimed at prevention and treatment of cerebrovascular diseases provide an objective basis.Methods: From June 2010 -2011 in January 169 hospitalized patients with cerebral infarction, according to whether patients with diabetes and hypertension were divided into 3 groups based on diagnostic criteria of hypertension 1999 World Health Organization (WHO) and the International High blood pressure League , hypertension treatment guidelines diagnostic criteria; diabetes diagnostic criteria based on 1999 WHO diagnostic classification criteria of diabetes. One diabetic group (n = 37 cases), hypertension group (n = 70 patients), diabetes combined hypertension group (n = 62 patients). 3 group patients on the medical history, general information, neurological deficit score (NIHSS) and blood lipids all items were analyzed. Application of Siemens Tim - avanto1.5T superconducting magnetic resonance system for routine head MRI (sagittal T1WI, T2WI, axial T1WI, T2WI), DWI and MRA examination, in order to analyze infarct location, size and responsibilities vascular distribution in each group .Results:1 General clinical data and neurological function:1.1 Average age :The group of patients with diabetes age of onset was 60.05±9.54 years of age, high blood pressure group was 62.28±9.56 years, and diabetes mellitus and hypertension was 62.93±8.45,no significant difference among the three groups (P> 0.05).1.2 Average blood pressure :The blood pressure in the diabetic group was 125.30±17.21/83.28±10.22 mm Hg, in the hypertension group was 153.75±18.65/90.79±10.67mmHg, and in the diabetic hypertension group the blood pressure was 162.1±17.34/93.75±13.03mmHg. The blood pressure in the hypertensive diabetic patients cohort were higher than the diabetes series and hypertension series.1.3 Fasting glucose:fasting blood glucose in the diabetes and diabetes hypertension was higher than the orther two ,compared to the three statisticaoldifferrence(p<0.5).2 Neurological deficit : The highest incidence infarct site were the periventricular , corona radiata and the basal ganglia. In the diabetic group , periventricular corona radiata infarction accounted for 53.18%, while basal ganglia infarction accounted for 20.23%.In the hypertension group, radiation periventricular Crown infarction accounted for 56.04%, while basal ganglia infarction accounted for 23.83%.In the diabetes combined hypertension group periventricular corona radiata infarction accounted for 52.19%, while basal ganglia infarction accounted for 24.06%,.No significant difference between the three groups (P> 0.05) .3 Features in MRI3.1The there groups were lacunar infarction on MRI manifestations, and were mainly concentrated in the middle cerebral artery areas . Followed by vertebrobasilar sites, respectively,they were 40.54% for the diabetes group, 47.10%for the hypertension group and 53.23% for the diabetes combined hypertension group, but no difference between the three. Distribution of blood vessels which occurred more than two cases of infarction, diabetes group accounted for 56.76%, the hypertension group accounted for 81.42% ,and the diabetes combined hypertension group accounted for 87.1%. There was a higher proportion in the hypertensive group and diabetes combined hypertension group ,and the two compared with the diabetic group were statistically significant (P <0.05).3.2 Three groups of patients were commonly multiple small focal cerebral infarction (diameter≤15 mm) ,and there namely were diabetic group 51.35%, hypertension group 71.43%, diabetes combined hypertension group 69.35% . Especially hypertension group and diabetes combined hypertension group, the two groups compared with the diabetic group, with statistical significance. The large area of infarction (diameter greater than or equal 40 mm) between the three groups no significant difference was significant (P> 0.05).3.3The three groups are mainly multiple infarct ,the proportion of multiple infarct were 67.56% for the diabetes group, 78.57%for the hypertension group,82.25% for the diabetes combined hypertension group, but the difference between the three groups was not significant (P > 0.05).Conclusion:①The blood lipid levels and blood pressure were high while diabetes combined cerebral infarction .The blood pressure of hypertension patients would be increased by diabetes , which increased brain vascular damage and caused cerebral infarction. .Multiple and small focal infarction were more common for diabetes combined cerebral infarction . Lesions were located in the middle cerebral artery area, and they were easy to concurrent two or more vascular territory infarction. Infarct location were mainly concentrated in the periventricular and corona radiata, followed by Is the basal ganglia. For the cerebral infarction patients without hypertension , there is a need for regular blood glucose testing system, or even tolerance test for the early diagnosis and treatment of diabetes, in order to reduce blood vessel damage, to prevent re-occurrence of stroke.
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