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The purpose of application of magnetic resonance angiography (MRA) the observed Leukoaraiosis (LA) in patients with intracranial vascular lesions, analysis of vascular risk factors. Methods 61 cases confirmed by brain MRI in patients with LA as the research object (LA group), as the control group (control group) and 44 normal elderly head MRI without LA All subjects underwent head MRA examination. Survey subjects of gender, age, educational level, history of hypertension, history of diabetes, history of cerebrovascular disease (CVD), smoking history, history of alcohol consumption, CVD family history; electrocardiogram to check the subjects measured blood pressure, fasting glucose, triglyceride (TG), total cholesterol (TCH), high density lipoprotein cholesterol (HDL-CH), low-density lipoprotein cholesterol (LDL-CH), fibrinogen (Fib) equivalents, and calculate body mass index (BMI), the application of mini-mental state examination (MMSE) subjects neuropsychological testing. Univariate analysis and logistic regression analysis of the relationship between LA and intracranial vascular lesions and vascular risk factors. Differences in age, MMSE scores between the LA group and the control group was significant (p lt; 0.001). Gender, level of education, body mass index, there was no significant difference (P gt; 0.05) LA group compared with the control group MRA: intracranial mixed circulatory disorder of the LA group compared with the control group was significantly increased (P lt; 0.01), the rate of abnormal blood vessels in the two groups, the number of diseased vessels, the existence of intracranial before and after circulatory disorder there was no statistically significant difference (P gt; 0.05) LA group, systolic blood pressure and history of hypertension was significantly higher than the control group (P lt; 0.05). The LA group other vascular risk factors such as: smoking, drinking, diabetes, CVD history, TG, TCH, HDL-CH, LDL-CH, Fib, ECG abnormalities, CVD family history have increased compared with the control group, but there was There was no significant difference (P gt; 0.05) LA group and the control group, two logistic regression analysis showed that: the mixed cycle intracranial lesions (OR = 5.663, 95% CI :1.511-21 .220, P = 0.010), history of hypertension (OR = 3.609, 95% CI: 1.155- 11.279, P = 0.027), age (OR = 1.085, 95% CI :1.026-1 .149, P = 0.005) into the regression equation factors had significant effects (P lt; 0.05) Conclusion intracranial mixed circulatory disorder, a history of hypertension and age is an independent risk factor of LA. LA patients with cognitive impairment.
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