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Provide the basis for Chinese medicine treatment of chronic hepatitis B and syndromes objective study of the relationship between the purpose: the syndrome distribution characteristics of chronic hepatitis B and TCM syndromes and virological indicators, biochemical indicators and B-. Methods: 221 patients with chronic hepatitis B patients in clinical collection Second Hospital of PLA, detailed records of clinical symptoms and clinical manifestations, divided into five card type: ① stagnation and spleen deficiency type; ② liver and gallbladder damp-heat; ③ liver blood stasis; ④ liver-kidney; ⑤ Spleen wet storm type. Cases of baseline data and laboratory parameters, including hepatitis B virus markers, liver function, B ultrasonic, chronic hepatitis B TCM syndrome distribution characteristics and the relationship between the laboratory parameters and B-. Results: 221 patients with chronic hepatitis B patients surveyed, TCM syndrome factors mainly to liver depression and spleen, TCM syndromes frequency followed by stagnation and spleen deficiency gt; liver and gallbladder damp gt; liver and kidney type gt; hepatic blood stasis gt; Spleen wet sleepy type. Age, sex, height, weight, duration, etc. There was no difference between the various syndromes (P gt; 0.05). . Divided into two groups according to the level of HBV DNA replication, greater than or equal to the 1.00 × 106copy/ml Group A, less than the 1.00 × 106copy/ml B group. Mainly to stagnation and spleen deficiency and liver and gallbladder damp-heat results showed that in group A (P lt; 0.01), a smaller proportion of hepatic blood stasis, liver-kidney and Spleen wet storm type. In group B, no difference in the proportion of the various syndromes gt; 0.05). Various syndromes, ALT, AST average level of the highest for the liver and gallbladder damp-heat, compared with the other four card type, P lt; 0.01, showed significant differences; followed by liver blood stasis, respectively, with the liver kidney and spleen wet storm type compared P lt; 0.05, there is a significant difference, but the difference between stagnation and spleen deficiency was not significant (P gt; 0.05) 4 TCM syndrome, serum total cholesterol red pigment (TBIL) and direct bilirubin (DBIL) the average levels of the most obvious of the liver and gallbladder damp heat, followed by liver blood stasis. Liver and gallbladder damp-heat compared with other syndromes, P = lt; 0.01, very significant difference; hepatic blood stasis type compared with the liver-kidney, P lt; 0.05, there is a significant difference. DBIL mean level in a very significant difference between the hepatic blood stasis Spleen wet storm type P lt; 0.01 5. Various syndromes, portal vein diameter and spleen thickness, there were no differences. Conclusion: According to the to designate distribution characteristics surveyed 221 patients with chronic hepatitis B permit analysis results show stagnation and spleen deficiency is the main pathogenesis of chronic hepatitis B; stagnation and spleen deficiency and liver and gallbladder damp-heat for chronic hepatitis B The main type of syndrome; stagnation and spleen deficiency and liver and gallbladder damp patients presenting with high hepatitis B virus replication status; damp-heat in liver and gallbladder inflammation of the liver in patients with severe damage; biochemical markers and HBV DNA levels can provide a reference for TCM syndrome of chronic hepatitis B .
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