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The Ultrasonic Integrated Strain Study of Healthy Beagle’s Left Ventricle During Cardiac Pacing

Author: LongBin
Tutor: YinLiXue
School: North Sichuan Medical College
Course: Medical Imaging and Nuclear Medicine
Keywords: Dog Left ventricular Cardiac pacing Echocardiography tracings surgery Strain
CLC: R445.1
Type: Master's thesis
Year: 2011
Downloads: 10
Quote: 0
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Abstract


Objective: This study attempts to the ultrasound velocity vector imaging (VVI) were measured in the healthy Beagles basal state and the right ventricular apex, left ventricular apex of the left ventricle sidewall pacing three cardiac cycle of the left ventricular wall segments direction of the timing of the heart, the subepicardial myocardial strain value: radial strain (radial strain, RS), circumferential strain (circumferential, CS) and longitudinal strain (longitudinal strain, LS) time series, as a the base derived the the myocardial strain vector (integrated strain, IS) time-series, in the establishment of the myocardial strain comprehensive vector IS foundation to explore the application of IS evaluation of cardiac pacing left ventricular segmental myocardial mechanical function of the clinical value of the state to be able to more accurate reflect the spatial characteristics of the different segments of the endocardial and subepicardial myocardial biomechanical state Beagles left ventricular wall. Materials and Methods: epicardial ultrasound echocardiography were collected from eight health thoracotomy than Beagles basis state and the right ventricular apex, left ventricular apex, left ventricular sidewall pacing the left ventricle standard mitral valve level, papillary muscle level and apex level, apical four-chamber, two-chamber and three-chamber view in three consecutive complete cardiac cycle within the real-time dynamic two-dimensional gray-scale image. Image frame rate gt; 70 frames / s. The resulting data into X-strain ultrasound workstation respective heart, were extracted from the 18 sections of the left ventricular wall, outer membrane myocardial mutually perpendicular radial strain (RS), the time series of circumferential strain (CS), and longitudinal strain (LS) parameters by the formula for the IS = √ RS 2 CS LS ~ 2 derived endocardial and epicardial strain vector time series (IS) parameters to obtain the integrated strain vector peak (the peak integrated strain PIS). Qualitative observations and compare different cardiac pacing left ventricular wall the myocardial segments strain vector trend and draw the strain vector - time curve. Parametric test to compare different state similar quantitative parameters; CS, RS, LS different pacing the left ventricular wall strain peak number of differences between segments with integrated strain vector pacing left ventricular wall peak strain differences Festival The segment number of rank-sum test. Results: ⑴ qualitative observations: RS, CS, LS time series parameters deduced IS time sequence parameters, can draw a left ventricular strain vector corresponding segments - time curve, you can visually see the strain integrated vector IS in different cardiac pacing state most of the time point of the absolute value of absolute values ??should be compared with other conventional variables changes, the more obvious changes in the strain - time curve. PCS (peak radial strain), PRS (peak circumferential) and PLS (peak longitudinal strain) appeared significantly higher than that of the left ventricular wall segments (2) quantitative parameter analysis: ① compared with the BASE state pacing state PIS significant differences significant difference in the number of left ventricular wall segments (P lt; 0.05). ② BASE state the PIS with three pacing state PIS left ventricular wall endocardium 18 myocardial segments the PIS in addition no statistical difference in sidewall segment of PIS in the remaining segments 2 - The state three kinds of cardiac pacing PIS differences (P lt; 0.05). 18 myocardial segments PIS In addition to the epicardium of the left ventricular wall and the base for wall segments basement sidewall, the sidewall apex before the interval three pacing PIS no statistical difference In the the cardiac pacing state of the remaining segments have 1-3 PIS differences (P lt; 0.05). Conclusion: The state of myocardial mechanical function of the left ventricular wall of healthy dogs is a complex integrated system. State of the segmental heart of the Institute in the development of the left ventricular wall, the inner and outer membranes of myocardial strain vector parameters may be able to be more sensitive than the traditional single strain components and reliable reflection of the left ventricle myocardial mechanics.

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CLC: > Medicine, health > Clinical > Diagnostics > Diagnostic Imaging > Ultrasonic diagnosis
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