|
Explore chronic hepatitis B family gathered on behalf of the syndrome type of infection with the hepatitis B virus markers, HBV DNA, liver function indicators, cross-referencing, TCM syndrome type and Western detection indicators to explore chronic hepatitis B virus hepatitis essence of TCM syndrome, the treatment of chronic hepatitis B for clinical dialectical objectification basis. Team of chronic hepatitis B TCM syndromes law study Case Report Forms CRF based on Traditional Chinese Medicine Hospital of Sichuan Province, Chengdu Infectious Diseases Hospital, West China Hospital 3 clinical outpatient units collected in patients with chronic hepatitis B, the CRF table four attending syndrome type information by five experts. All patients with chronic hepatitis B Western diagnostic criteria, inclusion criteria, exclusion criteria with reference to the December 2005 Hepatology of Chinese Medical Association and the Chinese Medical Association Infectious Diseases Branch, developed jointly with chronic hepatitis B prevention and treatment guidelines \The subject collected a total of 920 cases, five cases of invalid excluded due to the check indicators insufficiency, I divided into two groups according to whether the family infection, family history of infection group 314 cases, 601 cases of non-familial infection group and its comparative study . Detected in patients with hepatitis B virus markers, liver function, and the results were statistically analyzed using SPSS 13.0 statistical software. Results A total of cases, 915 were met the inclusion criteria, including 314 copies of HBV family history of infection, 601 copies of HBV family history of infection. The statistics: (1) HBV family infection group spleen deficiency syndrome, non-infected with HBV family history group mainly liver depression and spleen deficiency syndrome. (2) of HBV family infection history group without HBV family infection history group comparison: significant difference (P lt; 0.05), on the spleen-bit distribution without the liver, nephrotic bit distribution significant difference (P gt; 0.05 ); yang, qi deficiency and qi stagnation disease distribution on a significant difference (P lt; 0.05); higher frequency of 37 symptoms, although there was no significant difference (P gt; 0.05) but out in the two groups the top five of the same symptoms are related to the hot and humid; HBVM significant difference (P lt; 0.05), the HBV family infection group HBeAg positive rate in the family of non-HBV infection group the HBV family infection group HBeAb positive infection rate is lower than the non-HBV family group (P gt; 0.05); (3) a the HBV family history of infection with HBV family history of infection on behalf of the syndrome type in the average age of the hepatitis B virus markers, HBV DNA transaminase and bilirubin hormone, serum proteins comparison, there are significant differences (P LT; 0.01). (4) HBV family history group represents infection syndrome type and mean age and age, markers of hepatitis B virus, HBV DNA, transaminases, bilirubin and serum protein analysis, a significant difference (P lt; 0.01 ) Conclusion HBV family history of infection disease bit to the spleen, liver, kidney, which most closely spleen, kidney, main disease resistance yang, card type spleen deficiency syndrome. Spleen deficiency syndrome and other syndromes that group, the positive rate of HBeAg and HBV DNA viral load is high, prompted more active viral replication; significant correlation with TP, ALB, age less the the HBV family infection group was significantly younger consideration is due to congenital kidney yang qi deficiency, infected with HBV virus, evil Terma inside, spleen deficiency, can not drum evil to go out, so that the volt gas can not be outside the reach due. From the disease resistance of view, in addition to the virtual outside, mainly hot and humid, with HBV is contagious, considering the pathogenesis of the disease the kidney wet epidemic within the V.
|