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A Study on Influence of Pathology and Antioxidation Ability of Mouse Lung Tissue in Different Moxa-smong Environments

Author: Gu
Tutor: ZhongLan
School: Chengdu University of Traditional Chinese Medicine
Course: Acupuncture and Massage
Keywords: Ai smoke Concentration Smoked time Affect
CLC: R245.8
Type: Master's thesis
Year: 2011
Downloads: 53
Quote: 1
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Abstract

[Objective] To explore the impact of the Ai cigarette mouse lung tissue pathology and antioxidant capacity does not endanger the health of moxibustion use to provide a reference for the acupuncture clinic . 【Method according to the consulting room size moxa usage , and analog establish the different mouse Ai smoking environment . Kunming mice as experimental subjects were randomly divided into control group , low concentration of 4 weeks , the high concentration of 4 weeks , in a concentration of 4 weeks , the concentration of 2 weeks , in the concentration of one week group daily with a fine Ai Article smoked 3h, blank group not smoked . Observation and analysis of the pathological changes of the lung tissue sections at the end of the experiment , the detection and analysis of the white blood cell count and classification of the percentage of lung homogenates SOD and MDA . [ Results ] of lung : control group, the structure of the bronchus and lung were normal epithelial wall integrity, structured, the intrapulmonary vascular not no congestion and congestion , interstitial lung clearance no bleeding , edema and inflammatory cell infiltration . Low concentrations of 4 weeks is no exception ; concentrations 4 weeks group, bronchitis , congestion , bronchial hemorrhage ; high concentrations of 4 weeks is no exception ; concentration of 1 -week group vascular bronchial edema ; concentration of 2 weeks of no exception. The white blood cell count : each concentration group compared with the control group , the high concentration group was significantly higher ( P <0.01 ) than increased ( P <0.05 ) , 2 weeks , 1 week compared with significantly higher ( P <0.01 ) . The percentage of lymphocytes with blank group , increased low four groups , group , high four groups were more significant differences ( P <0.01 ) . The monocytes blank group , in four groups , lower there was a significant difference ( P <0.001 ) in group 2 . Granulocytes and neutrophils percentage of the control group, the low four groups reduce a significant difference ( P <0.001 ) in group 2 decreased more significant differences ( P <0.01 ) . The contents of SOD, MDA : high four groups in the 4 groups of SOD compared to the control group was significantly higher ( P <0.05 ) . MDA between groups was no significant difference ( P > 0.05 ) . [Conclusion] Ai smoke can mouse lung tissue edema , hyperemia , hemorrhage infiltrative inflammatory response and reduce lung tissue antioxidant capacity . The higher the concentration pathological sooner the longer the degree of injury is heavier and can repair itself after injury , but the mechanism is not explicitly related to the anti-inflammatory effects of smoke and Ai may still need further research . Clinical acupuncture clinic should pay attention to ventilation , lower smoke density , and the the moxibustion room time not too long .

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CLC: > Medicine, health > Chinese Medicine > Chinese medicine clinic > Acupuncture, acupuncture therapy > Moxibustion
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