Dissertation > Excellent graduate degree dissertation topics show

The Effect of Fatigue Load on the Lumbar Disc Morphology after Disectomy: A Pig Model

Author: FanZuo
Tutor: YuXiaoHua
School: Jiangsu University
Course: Orthopedics
Keywords: pig discectomy fatigue load discography disc morphology
CLC: R687.3
Type: Master's thesis
Year: 2009
Downloads: 22
Quote: 0
Read: Download Dissertation

Abstract


Objective:To investigate The effect of fatigue load on the lumbar disc appearance after discectomy by establishing the young pig model of disc fatigue load experiment after operation.Methods:4 samples of pig lumbar spines were selected and divided into two groups randomly:operative group during unilateral vertebral plate disectomy(group A) and control group(group B).Each group was dissected into 8 functional spinal units(FSU) and subjected to fatigue loading under the same parameter(the flexion angle was 9°,the rotation angle was 3°,the peak load was 3500N,the load frequency was 3Hz).Discograpy was taken on two groups before and after fatigue load experiment to measure the dimension of total disc,annuli fibrosi area,nucleus area and contrast agent area respectively.Frozen sections were taken on two groups after fatigue load experiment.Results:Total disc dimension of two group increased after load experiment (P<0.05).Group A showed that annuli fibrosi area increased(P<0.05) and nucleus area did not change after load experiment(P>0.05).Group B showed that annuli fibrosi area decreased(P<0.05) and nucleus area increased after load experiment(P<0.05).Contrast agent area in nucleus area of two groups increased after load experiment(P <0.05) and the proportion of Contrast agent area to nucleus area of group B was greater than that of group A after load experiment(P<0.05).No annuli fibrosi tear was found in two groups either by discography or by frozen section.Conclusions:The lumbar disc of young pig usually still can be able to bear a greater burden after discectomy and the physical structure of the disc may not be damaged seriously.The related function of young patients after discectomy have not declined significantly compared with the preoperative,which may be related to disc structure without significant damage after load experimnet.It provided the biomechanical foundation of animal experiments for explaining the clinical effects on young patients generally better than on elderly patients.

Related Dissertations

  1. Characterization and Identification of Maturity of Pig Manure Composting,S141.4
  2. Polymorphisms in the Promoter Region of Swine BMP7 Gene and Their Association with Reproductive Traits,S828
  3. Studies on Polymorphisms on Exon and Intron of BMP7 Gene and Their Associations with Reproductive Traits in Pigs,S828
  4. Study on the Combined Probiotics and Its Effects on Prodution Performance of Pigs,S828.5
  5. Study on Effect of Nutritional Regulation on Pig Production Performance and Discharge of Nitrogen and Phosphorus,S828.5
  6. Research of Resource and Recycling on Pig Excretion in Wenzhou,X713
  7. The Analysis on Technical Efficiency of Chinese Pig Production,F323.3
  8. Establishment and Application of Triple PCR Assay for Identification of Haemophilus Parasuis, Porcine Pleuropneumonia and StreptococcHS Suis Serotype 2,S858.28
  9. Study on the mRNA Expression Level and the Polymorphism of Follicle-Stimulating Hormone Receptor Gene in Taihu Pig’s Ovary,S828
  10. The Polymorphisms of TLR4 Gene and Function Analysis of C1027A in Suzhong Pig,S828
  11. Expression of β-Catenin in Pig’s Ovary and the Effect of β-Catenin on Porcine Granulosa Cells Apotosis and Steroidogenesis Related Enzyme,S828
  12. Investigation on the Diversity and Phylogenetic of Methanogens and the Relationship between Methanogenesis and Acetogenesis in the Hindgut of Pigs,S828
  13. Study on Establishment of Environmentally Friendly Industrial System of Pig Production,F326.3
  14. Transfer and Transformation of Cu in Black Soil-Crop System and In-sit Immobilization Mechanism,X53
  15. Effect of Maternal Dietary Protein Level on Fat Deposition in the Piglets at Weaning and the Research of Lipid Metabolism Regulation Mediated by Leptin,S828
  16. Tissue-Specific Expression and the Regulation of Porcine FTO,S828
  17. Study on the Territory of Blood Supply of One and Two Perforating Artery from the Same Rotation Pedicle in the Pig Flap,R622
  18. The Influence of Bile Duct Partial Obstruction on Guinea Pigs’ Sphincter of oddi in Early Stage,R657.4
  19. Scale Pig Breeding Production Process of Carbon Emission Calculation,F326.3
  20. Isoquinoline alkaloids SIPI409 Antiarrhythmic effect of,R965
  21. GXLC porcine encephalomyocarditis virus pathogenicity of strains,S858.28

CLC: > Medicine, health > Surgery > Orthopaedic Surgery ( movement system diseases,orthopedic surgery ) > Orthopedic surgery and surgery > Bone surgery
© 2012 www.DissertationTopic.Net  Mobile