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Objective: To investigate incision endometriosis clinical features, diagnosis, treatment, prevention, and disease-related factors. Methods: Part I: right 2002.1.1 ~ 2008.12.31 admitted the First Affiliated Hospital of Fujian Medical University, 30 cases of endometriosis incision clinical data were retrospectively analyzed and followed up to explore the incision endometriosis Clinical features, diagnosis, treatment, prevention and so on. Part II: using immunohistochemical streptavidin avidin - peroxidase (SP) was used to detect VEGF in endometriosis lesions and cuts P450arom the incision endometriosis lesions and surrounding fat tissue , abdominal subcutaneous adipose tissue cesarean birth and perineal incision under the adipose tissues to explore the occurrence of endometriosis incision related factors. Results: 1 incision endometriosis occurs in abdominal incision after cesarean section, the incubation period for about two years (average 23.5 months), transverse incision common, accounting for 75.0% (21/28 cases), especially right corner prone (76.2%, 16/21 cases), endometriosis lesions occurred in the subcutaneous fat layer (79.3%, 23/29 cases), with a single lesion more common; postpartum menstruation time, nursing time and latency there is a certain relationship; labor after cesarean section was significantly shorter than the incubation period not in labor (P lt; 0.05); mass size, depth of invasion has nothing to do with the course, but not with postoperative recurrence, B super high preoperative diagnosis , amounting to 96.30% (26/27 cases), CA125 testing clinical significance. 2, P450arom incision endometriosis in the surrounding adipose tissue was significantly higher than cesarean incision under lateral abdominal wall and perineum adipose tissue expression (P lt; 0.05), while the abdominal incision cesarean subcutaneous adipose tissue than episiotomy ( P lt; 0.05), incision endometriosis in ovarian P450arom expression was not significantly cyclical differences (P gt; 0.05); VEGF incision endometriosis in the expression of ovarian cyclical follicular phase was significantly higher than luteal phase (P lt; 0.05), and recurrence, a large mass was significantly higher than those without recurrence, a small mass group (P lt; 0.05). Conclusions: The incision endometriosis occurrence and iatrogenic factors, but also with their own factors. The incidence of pregnancy was significantly higher than cesarean birth episiotomy, may be associated with abdominal fat layers P450arom pregnancy was significantly higher than the perineum organizations. Reduce the cesarean section rate, abdominal incision surgery to protect and improve operative techniques, postpartum lactation six months or more to help reduce the incidence of this disease. Treatment with surgery, choose a relatively low expression of VEGF localized lesions premenstrual surgery may help reduce relapse, especially for deeper, larger lesions, their premenstrual obvious, easy to achieve adequate resection. Cutting edge clean, is the key to preventing relapse.
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