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Objective: To establish an animal model of a low body temperature renal bullets penetrating injuries after injury comparing a line partial nephrectomy (PN) and line packing method of treatment effect in the animal model. : Four small pig spleen and right kidney removed, and rectal temperature fell to 34 ° C, 1/3 at the center position of the left kidney under experimental model gun injury. The record after injury, mean arterial pressure (MAP), and observed five minutes after the injury and death, blood loss (BL) and changes in body temperature (T), before and after the death of hemoglobin (Hb), pH (PH) and lactic acid (LA ) changes. Animal model of 15 miniature pigs were randomly divided into partial nephrectomy (PN) group the perirenal tamponade (PP) group and ballistic tamponade (IP) group. Compare operative time (OT), 1 hour after injury, blood loss (BL1h), one hour after the injury body temperature declines the (△ T1h), one hour after the injury fluid volume (FIA), the survival time after injury (AT) and other indicators in all The variation between the groups and different. Results: ① small pig hurt after five minutes of mean arterial pressure (MAP5) to 73.25 ± 7.455mmHg, decreased 47.75 ± 4.500mmHg, about the basis of mean arterial pressure (MAP0) 60.5%. ② hurt after five minutes of blood loss (BL5) for 311.50 ± 43.147g, death, blood loss was (BLd) 781.50 ± 78.928, BL5 accounted for 39.9% of the total blood loss. ③ injury five minutes after the temperature drops value (△ T5) of 0.050 ± 0.0577 ° C, while the temperature drops in the death value (△ Td) of for 1.075 ± 0.1258 ℃. ④ animal deaths, Hb by injury before 114.50 ± 5.447g / L to 84.25 ± 5.909 g / L (P lt; 0.01), LA from preinjury 1.750 ± 0.7853 mmol / L, rose to 9.950 ± .6035 mmol / L (P lt; 0.01), PH from reduced 7.1325 ± 0.12580 7.4075 ± 0.06238 (P LT; 0.05). ⑤ renal pathology of change for obvious primary injury Road area, contusion area and oscillation region. ① OT PP and IP group (19.60 ± 3.647 vs 15.20 ± 2.775min) and FIA (1140.00 ± 272.489 vs 930.00 ± 189.077ml) no significant difference (P gt; 0.05), but significantly lower than the PN group (80.00 ± 9.354min, 1860.00 ± 281.514ml) (P lt; 0.01). ② PP and IP groups elevated body temperature than the injury of one hour after the injury, △ T1h is negative, there is no significant difference between the two (-0.140 ± 0.4827 vs -0.380 ± .6301 ° C) (P gt; 0.05), are significantly less than that the PN group the △ T1h of value (1.380 ± 0.4087 ° C) (P lt; 0.01). ③ IP group BL1h (118.00 ± 11.136g) was significantly less than the PP group (158.80 ± 27.725g) (P lt; 0.01), but the PN group (136.40 ± 19.832g) with PP or IP group is not significantly different (P gt ; 0.05). The ④ PP group (2.125 ± 0.6292d) AT significantly longer than the PN group (0.625 ± 0.6292d) (P lt; 0.05), no significant difference between (P gt IP group (1.500 ± 0.7071d) between PP or PN group; 0.05). ⑤ after injury, creatine kinase (CK), aspartate aminotransferase (AST) have dramatically increased, alanine aminotransferase (ALT), creatinine (Cr), blood urea nitrogen (UN), the rapid increase in bladder pressure (BlaP) was also significantly higher. Conclusion: ① successful use of pig animal model to establish a low body temperature renal bullets penetrating injuries. The ② injury to the requirements of the DCS, DCS in the kidney trauma research by the model. ③ the homemade experiments with simulated guns to solve a the gunshot wounds simulation authenticity, accuracy, repeatability and security issues, can better simulate gunshot wounds. ① obliteration and partial resection of a renal hemorrhage control effect similar to the obliteration of the operative time is shorter, better to avoid the loss of body heat, less fluid volume after injury, and survive longer. ② ballistic tamponade than perirenal tamponade can better control the bleeding, but they can be used as an option when the damage control of renal trauma. ③ To prevent severe trauma IAP increased as well as the occurrence of ACS, when there are difficulties in the abdomen was closed for temporary abdominal closure. The ④ CK and AST reaction indicator of the severity of the trauma, post-traumatic quickly increased in the short term to indicate increased mortality. Should avoid repair surgery in CK and AST rising downstream uncertainty.
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