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Objective: To observe the ney Guchong decoction the efficacy of the kidney puberty uterine bleeding bleeding , from the theoretical , clinical , animal experiments to investigate the hemostatic mechanism . Methods: Clinical study : 60 patients were randomly divided into 2 groups : the treatment group and the control group . Be separately the ney solid punch soup Gongxuening oral capsule . Observe the time for the two groups of patients with vaginal blood , primary and secondary symptoms before and after treatment to improve the situation , the cycle of blood Hb content before and after treatment , blood fibrinogen , serum Ca2 content , menstrual blood prostaglandin ( 6- K -PGF1α , TXB2 ) content and treatment before and after the changes in endometrial thickness . Experimental research : observation Zishen solid punch soup of Dealt animals out clotting time , uterine ER , PR number of impact and the impact of not modeling animals isolated uterine contraction . Results: Clinical Research : hemostasis significant cure rate : 83.3% of the treatment group and the control group, 46.7% (P lt; 0.05); syndromes significantly more rate : 86.7% of the treatment group and the control group, 40 % ( P lt; 0.05 ) ; treatment after two sets of indicators of primary and secondary disease , blood fibrinogen , serum Ca2 menstrual blood Hb content , menstrual blood prostaglandin levels , endometrial thickness changes were significant differences (P lt ; 0.05 , P lt; 0.01) . Experimental study : the ney solid red soup can shorten the animal model of the clotting time , reduce ER, PR levels and promote normal animals isolated uterine contraction . Conclusion : Kidney Guchong soup to treat kidney puberty uterine bleeding , hemostatic effect and its mechanism of procoagulant promote contractions , regulating the proportion of prostaglandins , reduce ER, PR and other aspects related to .
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