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Objective To study the coronary heart disease with stable angina pectoris part of TCM type (heart blood stasis, phlegm congestion certificate, qi stagnation cardiothoracic card) endothelial function in patients, including blood nitric oxide (NO), endothelin (ET) , von Willebrand factor (vWF), thrombomodulin (TM) level and brachial artery flow-mediated dilatation (FMD) and nitroglycerin-mediated vasodilation response (NMD). Research Methods August 2007 to January 2009, 90 cases of treatment of patients with stable angina pectoris in the Guangdong Provincial Hospital Heart Center, divided into blood stasis group, phlegm congestion Group, qi stagnation minded group of 30 cases, normal control group of 20 patients, brachial artery flow-mediated vasodilation function and nitroglycerin-mediated vasodilation detected by ultrasound method using enzyme-linked immunosorbent assay (ELISA) or nitrate reductase assay of plasma ET-1, vWF, TM, and NO, to analyze the relationship between the various syndromes endothelial function and TCM syndromes. The results are compared with the control group, three groups of patients have a lower FMD (P <0.05), blood stasis group was the lowest, compared with phlegm congestion group, qi stagnation minded group, there was significant difference ( P <0.05); compared with the normal control group, phlegm congestion Group, qi stagnation minded group, patients with blood stasis group has a lower NMD (P <0.05); compared with the control group, three groups of patients were lower NO (P <0.05), the lowest group of blood stasis, qi stagnation minded group, there was significant difference (P <0.05); compared with the control group, qi stagnation minded group, the heart and blood stasis resistance group, phlegm congestion in patients with higher ET (P <0.05), blood stasis group was the highest, compared with phlegm congestion group, there was significant difference (P <0.05); phase with the other three groups than patients with blood stasis group the higher vWF (P <0.05); compared with normal control group, the three groups of patients with higher TM (P <0.05). The emergence of blood stasis group as the dependent variable, Binary Logistic regression analysis, the results showed FMD protective factors the (OR FMD = 0.159), age of risk factors the (OR Age = 1.325). FMD as the dependent variable, stepwise linear regression analysis, the results show the NO protection factors (OR , NO = 0.261), ET, TM, vWF, age, risk factors (OR et = -0.447, the OR TM = -0.241, OR vWF = -0.176, OR the Age = -0.139). FMD and NMD, no between there was a significant positive correlation (P <0.01); the FMD with ET, vWF, TM, there was a significant negative correlation (P <0.01). Between the different syndromes of the conclusion of the study, the patients with the different endothelial function, blood stasis endothelial function in patients with the lowest phlegm congestion, qi stagnation followed by cardiothoracic patients; FMD for blood stasis angina occurred protective factors, the age of its the risk factors; FMD and NMD, no inter-exist significant positive correlation FMD and ET, vWF, TM, there was a significant negative correlation.
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