|
Objective: To observe Ginsenosides combined with glucocorticoid hormones control the clinical efficacy of nephrotic syndrome , verify that the ginsenosides enhanced view of the glucocorticoid effect . Methods: A randomized, double-blind controlled study . 120 patients with nephrotic syndrome were randomly divided into two groups , were given on the basis of conventional prednisone ginsenoside capsules 50 mg / 2 times / day and placebo capsules 50mg / times, 2 times / day , treatment 12 months. Laboratory indicators of the TCM clinical symptoms observed before and after treatment of patients with nephrotic syndrome , liver and kidney function , blood lipids , serum albumin , 24-hour urine protein quantification , hormones reduction and overall clinical efficacy . Results: ginsenoside group in the overall clinical efficacy of the treatment of NS to improve clinical medicine total symptom score and symptom score , the effect is superior to the placebo group ( P lt ; 0.05 , P lt ; 0.01 ) ; reduce the 24-hour urine protein quantitative aspects of the effect of significantly compared to the placebo group ( P lt ; 0.05 ) ; the ginsenoside group prednisone reduction rate than the placebo group was significantly ( P lt ; 0.05 ) ; in mitigating the adverse effects of glucocorticoid effects are excellent in the placebo group ( P lt ; 0.05 ) . Conclusion: Ginsenoside can enhance the clinical effect of glucocorticoid treatment NS , reduce glucocorticoids clinical dosage .
|