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Objective: This paper compares hemoglobin A1c levels ≥ 6.5 ℅ and lt; 6.5 ℅ two groups of patients with sudden deafness clinical data, hearing loss characteristics and efficacy study hemoglobin A1c with sudden deafness relationships, and glycosylated hemoglobin A1c checked in patients with sudden deafness in significance. METHODS: ① Clinical data: collected from January 2009 to December 2010 at the Second Affiliated Hospital of Dalian Medical University ENT duration of hospitalization in a month or less of patients with sudden deafness. ② grouping method: Place all of sudden deafness diagnosed patients admitted to hospital two days after checking fasting glycosylated hemoglobin A1c. The glycated hemoglobin A1c ≥ 6.5 ℅ into the test group of patients, lt; 6.5 ℅ into the control group of patients. Because the test group were patients aged ≥ 38 years of age, the age factor to exclude the interference of the Age lt; 38 years of age and hemoglobin A1c lt; 6.5 ℅ patients excluded. Experimental group was 59 cases, a total of 70 ears. Including 25 males and 34 females. Left ear 30 cases, 26 cases of right ear, both ears while the incidence seven cases (total 14 ears). The control group was 58 cases, a total of 61 ears. There were 22 males and 36 females. Left ear in 26 cases, 29 cases of right ear, both ears while the incidence three cases (total 6 ears). ③ diagnosis is based on: For all study subjects pure tone audiometry examination (PTA), distortion product otoacoustic emissions (DPOAE), auditory brainstem response (ABR), the internal auditory canal CT examination, according to the patient's history and above examination to exclude retrocochlear lesions , a clear diagnosis. Audiological test results were compared characteristics. ④ All patients were treated with currently accepted comprehensive treatment. Pay attention to rest, adequate sedation, aggressive treatment of related diseases, such as hypertension, hyperthyroidism and so on. Class of drugs used to improve circulation, neurotrophic drugs and lipid-lowering therapy to anticoagulation. Both glucocorticoid and auxiliary hyperbaric oxygen therapy. Where severe and very severe sensorineural deafness patients while giving Batroxobin. 10 days for a course of treatment after the review by a pure tone audiometry examination, based on pure tone audiometry before and after treatment in return checking Analysis effect. ⑤ Statistical Methods: Using SPSS17.0 software package, the two groups of patients according to gender, age, hearing-impaired ear, hearing graphic, hearing loss degree of hearing recovery after treatment, such as numerical variables were statistically described. Results: (1) the sex between the two groups before treatment compared to the incidence of ear hearing loss showed no statistical significance. Test group the proportion of patients with binaural onset than the control group, but the difference was not statistically significant. (2) Before treatment, degree of hearing loss, the difference was statistically significant (X ~ 2 = 22.599, P lt; 0.01), the experimental group the proportion of patients with moderate hearing loss up to the control group, the proportion of patients with mild hearing loss up . In accordance with the classification of hearing graphics, high-frequency hearing loss groups are heavier descending audiogram maximum difference between two groups was not statistically significant (X ~ 2 = 4.265, P gt; 0.05). Losses at each frequency hearing threshold difference was statistically significant (P lt; 0.05), which 8KHz difference was statistically significant (F = 1.230, P lt; 0.01) (3) Comparative efficacy differences between the two groups after treatment with statistically significant (X ~ 2 = 26.549, P lt; 0.01). (4) After treatment 4KHz and 8KHz Listening to improve the situation was no significant difference (4KHz: F = 0.000, P gt; 0.05; 8KHz: F = 0.809, P gt; 0.05). Conclusion: 1, HbA1c in patients with sudden deafness ear hearing loss has nothing to do, nothing to do with sex. 2, HbA1c sudden rise will increase the degree of hearing loss, deafness, affecting sudden deafness. 3, high-frequency hearing recovery and the initial degree of hearing loss, has nothing to do with HbA1c levels. 4, to give patients with sudden deafness hemoglobin A1c testing can help early diagnosis of diabetes, and patients with diabetes understand glycemic control. Can also be used as an estimate prognosis of sudden deafness reference indicator for clinical comprehensive treatment to take timely measures, has a positive significance.
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