|
Objective To observe the spleen-deficiency type polycystic ovary syndrome (PCOS) patients with clinical features, and related reproductive hormones, some glucose and lipid metabolism indicators. Methods 108 cases of PCOS patients, including 69 cases of spleen deficiency type spleen group, 39 cases of non-spleen-deficiency type non-SDS group; another to select the same healthy women ages 20 cases of the control group. Groups were detected serum luteinizing hormone (LH), follicle-stimulating hormone (FSH), estrogen (E 2 ), testosterone (T), sex hormone binding globulin (SHBG), fasting and after blood glucose (FBG, PBG), fasting insulin (INS), total cholesterol (TC), triglyceride (TG), high density lipoprotein (HDL), low density lipoprotein (LDL), the level of leptin (Leptin); measuring the body mass index (BMI), waist-to-hip ratio (WHR) diet, living history questionnaire and TCM syndrome score in each group, the differences between the observed indicators of the group. SDS group analysis of blood stasis, phlegm syndrome. Spleen group of 32 patients, spleen and replenishing qi intervention in March, before and after treatment the assessment Deficiency Syndrome candidate score and all indices. 1 three groups part of the Reproductive Endocrinology and Metabolism comparison: the the SDS group of BMI, WHR were higher than that in the control group (p <0.05 ~ 0.01), slightly higher than the non-SDS group (p> 0.05). Spleen group T FT were higher (p <0.01), and SHBG lower than the control group (p <0.01); the SDS group T, SHBG slightly below non Spleen groups, FT slightly higher than the non-SDS group (p > 0.05). The SDS group E 2 / T lower than the control group (p <0.01), LH, LH / FSH groups was higher than that of the control group (p <0.01); the SDS group with non spleen deficiency group difference (p> 0.05); the SDS group FBG, PBG, INS, Homa-IRI was significantly higher (p <0.01); Spleen group FBG, PBG compared with the non-SDS group have a high tendency; INS, Homa-IR was significantly higher than that SDS group (p <0.01); the spleen group of TC, TG, LDL, Leptin were higher than that in the control group (p <0.05 to 0.01), compared with non-SDS group also have a high tendency. 2 SDS group syndrome characteristics: various syndromes frequency higher order body tired fatigue (73.9%), bowel the sagittal gas (65.2%), and abdominal distention after eating (60.9%); food is not followed Festival diarrhea (55.1%) and sleeping salivation (52.2%). SDS group may be a relevant factor in the incidence analysis: Ridit inspection SDS group with the control group (p <0.05), the former is more inclined to poor eating and sleeping habits in diet, sleep time. SDS group before and after treatment: patients with BMI, WHR, T, FT, LH, LH / FSH, INS, Homa-IRI, Leptin and treatment than are varying degrees downward (p <0.05 to 0.01); SHBG raised (p <0.05); FBG, PBG, TC, TG, compared with before treatment than before treatment also decreased (p> 0.05); frequency syndrome and ratings are lower than before treatment. Conclusion 1. Deficiency Syndrome PCOS syndrome type temper with PCOS occurrence important; 2 body tired fatigue, bowel vector gas and bloating after eating waiting for evidence of spleen-deficiency type PCOS patients; the INS, Leptin abnormalities may kang Granules PCOS formed the material basis for one; 4. Spleen Qi method can improve the spleen-deficiency type patients with PCOS syndrome and to promote the material and energy metabolism.
|