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Early Diagnosis and Quantitative Evaluation of DWI in the Lesions After Radiofrequency Ablation of Hepatic Carcinoma

Author: RenXiaoZuo
Tutor: DuDuanMing
School: Shantou University
Course: Medical Imaging and Nuclear Medicine
Keywords: Diffusion Weighted Imaging Hepatic carcinoma ADC values Radiofrequency ablation
CLC: R735.7
Type: Master's thesis
Year: 2011
Downloads: 71
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Abstract


Objective: To study the magnetic resonance diffusion weighted imaging (DW-MRI) in the early diagnosis of residual tumor after radiofrequency / recurrence or new lesion and radiofrequency ablation lesions tissue components quantitative evaluation value. Materials and Methods: 31 cases of patients with hepatocellular carcinoma radiofrequency ablation (RFA) preoperative and postoperative, and 20 cases of normal control group DW-MRI data analysis, observed DWI of liver cancer the RFA after surgery lesions show and DWI and ADC map signal changes of the region of interest (ROI), before RFA lesion ADC values ??measured on ADC maps and RFA ablation ADC values ??of different organizations within the stove, and the pathology or DSA image control, ADC threshold values ??for various tissue components. Results: analysis CT images of 28 cases and 31 cases of RFA treatment before magnetic resonance scan enhance the the DWI image sensitivity, specificity, PPV and NPV, results showed that magnetic resonance scan enhanced (100%) combined with the sensitivity of DWI. 31 patient scans showed b values ??select 600 and 800 s / mm ~~ the DWI images show a more accurate signal of liver lesions and lesion. Of 38 lesions in 31 patients before and after RFA treatment MRI scan, enhanced the DWI image analysis and ADC value measurement. Overall measurement method and the measurement of the high and low signal area, the difference between the value of 800 s / mm to 2 ADC map, liver lesions measured ADC values ??of normal liver parenchyma ADC value b, respectively, with a significant sex (P lt; 0.05 ); b values ??of 600 and 800 s / mm ~ 2 ADC map measured, respectively, with a significant difference between ADC values ??of liver lesions and surrounding liver tissue, liver tumors and inflammatory response organizations, as well as liver tumors RFA preoperative and postoperative sex (P lt; 0.05); b value of 400 s / mm ~ 2 measured ADC map was liver lesions and surrounding liver tissue, liver lesions and inflammatory response organizations and liver lesions RFA preoperative and postoperative ADC value no significant differences (P gt; 0.05); 400, 600 and 800 s / mm ~ 2 ADC map measured RFA of liver lesions after coagulation necrotic tissue, liver lesions liquefied necrotic tissue ADC value b value between the differences were statistically significant (P lt; 0.05). Conclusion: DWI tumor sensitivity combined the MRI applications can improve the detection of liver lesions. Lesions show a clear premise, try to select the ADC map, the measured value of 800 s / mm ~ 2 b ADC values ??close to the real DC value. DWI combined with ADC map to display the signal difference between the tumor and normal liver parenchyma, inflammatory tissue and necrotic tissue, and each organization has a specific range of the ADC value, quantitative evaluation of the efficacy of RFA treatment.

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CLC: > Medicine, health > Oncology > Gastrointestinal Cancer > Liver tumors
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