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Clinical Research on Electrical Stimulation Therapy of Denervated Skeletal Muscle Atrophy by Peripheral Nerve Injury

Author: ZhangJinBao
Tutor: LiangBingSheng
School: Shanxi Medical
Course: Hand Microsurgery
Keywords: Electrical stimulation therapy Denervation Skeletal muscle atrophy
CLC: R651.3
Type: Master's thesis
Year: 2009
Downloads: 108
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Abstract


Objective: peripheral nerve injury induced skeletal muscle atrophy through electrical stimulation treatment of early postoperative follow-up after treatment EMG findings and clinical specialist examination strength, sensory function recovery, the results were statistically analyzed to assess efficacy. Early observations of electrical stimulation on denervated skeletal muscle atrophy recovery implications for clinical prevention and treatment to provide a reference to further improve the clinical efficacy of the treatment of skeletal muscle atrophy, thereby reducing the loss of skeletal muscle function. Methods: orthopedic hospital from April 2007 to October 2008 were treated peripheral nerve injury in 60 patients, of which 30 cases were randomized to receive electrical stimulation therapy, and the other 30 cases neurotrophic drugs and physical therapy. Electrical stimulation therapy in 30 patients, 14 cases of radial nerve injury, median nerve injury in 10 cases, 6 cases of ulnar nerve injury after injury 6 hours to three months hospitalized surgical exploration, surgical release 10 cases, 15 cases of direct anastomosis, nerve graft anastomosis five cases; after 3 days, with Shanghai production NDI500 type EMG implementation of surface neuromuscular electrical stimulation therapy, the use of appropriate stimulation frequency (2 ~ 5Hz). Stimulate parts: from the proximal anastomosis neurolysis or 3 ~ 5cm, the principle of the surface electrode as close as possible to the nerve and muscle nerve dominated by muscle stimulation therapy at the belly; stimulus intensity: 20 ~ 30mA, and to patients with resistant subject to standard; stimulation time: Each site irritation 5min, first conduct three cycles of electrical stimulation therapy, the first course of treatment: 2 times / d, spacing 2d, of a month; first course of a 2,3 times / d, interval 2d, a total of two months, while assisting patients with active and passive muscle contractions. Another 30 cases of patients with neurotrophic drugs and physical therapy, including 11 cases of radial nerve injury, median nerve injury in 13 cases, 6 cases of ulnar nerve injury after injury 6 hours to 3 months hospitalized surgical exploration, surgical release 12 cases, direct anastomosis in 14 cases, 4 cases of nerve graft anastomosis; drug therapy: oral vitamin B1, vitamin B6 each 10mg, 3 times / d, mecobalamin 500μg, intramuscular injection every other day, sustained in January; Movement Therapy: According to different strength, phases, the lower extremity and hand-functional training. Two groups of patients before and after treatment, respectively, and specialist EMG examination followed up for 6 months, follow-up rate of 100%. EMG before and after treatment outcome changes, and neuromuscular electrical stimulation therapy in patients with muscle strength, sensory function improvement, based on clinical evaluation standard, combined with statistical significance for therapeutic efficacy. Results: (1) electrical stimulation treatment group and the control group compared to the results EMG: denervation potentials significantly reduced the number of cases, new potentials and motor unit potential regenerative potential and the number of cases increased significantly, and the emergence of more potential cases raise complex count, while MCV, SCV more significant increase in the number of cases, statistical composition ratio (P lt; 0.001) meaningful, indicating that electrical stimulation treatment group improved EMG has clinical value. (2) sensory recovery after treatment, compared to the situation: Statistics composition ratio (P lt; 0.05) meaningful, electrical stimulation therapy group recovery rate of 70% recovery rate of 40% of the control group, the former significantly more improvement, the recovery rate was (P = 0.020 lt; 0.05) sense. (3) muscle recovery after treatment was statistically constituent ratio (P lt; 0.05) meaningful, electrical stimulation therapy group recovery rate of 80%, recovery rate of 50.0% in the control group, the former is significantly more improvement, statistical recovery rate (P = 0.028 lt; 0.05) makes sense. (4) electrical stimulation group and control group compared two groups good rate, composition ratio was statistically significant (P lt; 0.05), electrical stimulation excellent rate of treatment group was 83.3%, excellent rate of 43.3% in the control group, two groups were statistically significance (P = 0.001 lt; 0.05). Description The former is superior to the latter, the electrical stimulation group of patients recover faster. Conclusion: Peripheral nerve injury induced skeletal muscle atrophy, early postoperative neuromuscular electrical stimulation therapy can promote functional recovery of damaged nerves, prevent muscle atrophy, increase the cure rate and reduce morbidity. Electrical stimulation therapy clinically proven efficacy, than a simple exercise therapy with drugs the effect is obvious, for the clinical treatment of peripheral nerve injury induced skeletal muscle atrophy to provide effective way.

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CLC: > Medicine, health > Surgery > Of surgery > Head and Neurosurgery > Peripheral nerve
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