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The Relationship between Atherogenic Index of Plasma, Central Aortic Pressure and Nonvalvular Atrial Fibrillation

Author: ZhangZuo
Tutor: LiGuangPing
School: Tianjin Medical University
Course: Internal Medicine
Keywords: Non - valvular atrial fibrillation Paroxysmal atrial fibrillation Chronic atrial fibrillation Plasma induced atherosclerosis index Central aortic pressure Left atrial diameter
CLC: R541.75
Type: Master's thesis
Year: 2011
Downloads: 27
Quote: 0
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Abstract


Purposes through history, electrocardiogram, echocardiography, and other tests, the selected object is divided into non-valvular atrial fibrillation (AF) patients with and without AF control group, paroxysmal AF and chronic AF AF episodes characteristics in accordance with the object of study is divided into two alkylene group. Induced atherosclerosis index (AIP) between the two groups of non-valvular AF group and AF control group plasma lipid profile level, right arm brachial artery blood pressure and other risk factors for the level of comparative analysis to explore the AIP on non-valvular the sexual AF occurred; 2. further analysis of paroxysmal AF group and without AF control group 2, group centers arterial pressure (CAP), the differences in the AIP, the level of lipid profile and other related indicators, research the CAP and the AIP with paroxysmal AF relations; against hair AF, the AIP, lipid profile between the two groups of chronic AF level, right arm brachial artery blood pressure and other risk factors in the level of comparative analysis, to further explore the impact of the development of the non-valvular AF, the outcome of possible factors. Methods selected Stayed August 2009 to October 2010, 312 cases of Tianjin Medical University Hospital cardiology patients, detailed records study of age, gender, history of hypertension, smoking history, history of coronary heart disease, ECG, echocardiography discharged HDL-C), low-density lipoprotein (?) (LDL-C), liver function (EDX) and fasting plasma glucose conventional biochemical parameters, and in accordance with the formula to calculate body mass index (BMI) and AIP indicators. Omron HEM-9000AI central aortic pressure meter measurement used simultaneously and record the center of the AF control group and patients with paroxysmal AF group systolic blood pressure (CSBP), radial artery systolic pressure (SBP2), the gain index (AI), heart rate (HR) pulse pressure (PP) indicators. Enrolled patients were divided according to the history, electrocardiogram and echocardiography examination results with non-valvular AF group and AF control group, and divided into two subgroups of paroxysmal AF and chronic AF AF episodes characteristics based. Results of a non-valvular AF patients age, the proportion of smoking, coronary heart disease prevalence, DBP, HR, right ventricular diameter, left ventricular systolic diameter, posterior wall thickness, left atrial diameter, TG, VLDL-C, BMI, AIP were significantly higher than the control group without AF, and HDL-C levels and ejection fraction (EF) was lower than the AF control group (P lt; 0.05). Between the two groups the prevalence of hypertension, the proportion of males, SBP, TC, LDL-C level difference was not statistically significant (P gt; 0.05). Nothing more than valvular AF as the dependent variable, the ratio of age, smoking, coronary heart disease, the prevalence of left atrial diameter, DBP, HR, EF, TG, HDL-C, BMI,, the AIP and other factors as independent variables Binary logistic regression The analysis shows: age, posterior wall thickness, the size of the left atrium, HR, AIP, TG, DBP into the regression equation, and prompts the AIP, DBP, age, left atrial diameter non-valvular AF important impact factors (P lt; 0.05). 2. Nonvalvular paroxysmal AF group suffering from age, right ventricular diameter, left atrial diameter, SBP2, CSBP, AI, TG, BMI,, the AIP water on average significantly higher than the control group without AF, and HDL-C levels below AF control group (P lt; 0.05). Hypertension prevalence of coronary heart disease in the two groups the prevalence of male ratio, the proportion of smoking, posterior wall thickness, left ventricular systolic diameter, HR, SBP, DBP, PP, EF, TC, LDL-C, VLDL-C levels the difference was not statistically significant (P gt; 0.05). Binary Logistic regression analysis showed nothing more than valvular paroxysmal AF as the dependent variable, and age, left atrial diameter, SBP2 CSBP, AI, TG, BMI, the AIP and other factors as independent variables: left atrial diameter, AIP, TG, SBP2 were entered into the regression equation and prompt AIP SBP2 important factors for left atrial diameter non-valvular paroxysmal AF (P lt; 0.05). Continuous AF in patients with non-valvular age, the rate of coronary heart disease, left ventricular systolic diameter, posterior wall thickness, left atrial, right ventricular diameter, DBP, HR were significantly higher than those in non-valvular paroxysmal AF control group EF level lower than non-valvular paroxysmal AF group (P lt; 0.05). Between the two groups the prevalence of hypertension, smoking rates, the proportion of males, left ventricular diastolic diameter, BMI, TG, HDL-C AIP, SBP, TC, VLDL-C, LDL-C level difference was not statistically significant (P gt ; 0.05). Elevated to a certain extent affect the occurrence of non-valvular AF the conclusion 1.AIP value, and may be one of non-valvular paroxysmal AF important influencing factors; 2.CAP level rise may be associated with non-valvular there is a certain relationship between the occurrence of paroxysmal AF; age rate of coronary heart disease, left ventricular systolic diameter, posterior wall thickness, left atrial, right ventricular diameter, DBP, HR, EF may to some extent affect non-valvular the development of AF.

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CLC: > Medicine, health > Internal Medicine > Heart, blood vessels ( circulatory ) disease > Heart disease > Arrhythmia > Atrial fibrillation and atrial flutter
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