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The Research of Detection Rate of Prostate Cancer with Biopsy by Transrectal Contrast Enhancement Ultrasound

Author: YeZhiMin
Tutor: LiuXueMing
School: Zhejiang University
Course: Ultrasound diagnostics
Keywords: Transrectal ultrasonography Detection rate Guided biopsy System puncture Prostate Cancer
CLC: R445.1
Type: Master's thesis
Year: 2011
Downloads: 55
Quote: 0
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Abstract


Objective: To compare transrectal ultrasonography-guided biopsy system with a single biopsy (8 stitches) detection rate of prostate cancer research, a clear transrectal ultrasonography for diagnosis of prostate cancer. Methods: 90 cases of prostate cancer patients with suspected prostate first line after transrectal ultrasonography (TRUS), then transrectal ultrasound imaging (TRCEUS), was high on contrast enhancement patterns of suspicious lesions suggestive of its first implementation-oriented biopsy , and then the remaining parts of the system given conventional biopsy obtained results of their inspection methods and pathological control (such as angiography and conventional systems prompted biopsy of suspicious sites are similar or identical parts, and the pathological results suggest positive patients, then the results of two Methods are added one case of positive cases), comparing the two puncture method for prostate cancer detection rate differences. Another 90 patients for ultrasound contrast imaging applications Yum imaging analysis software (Qontrast 4.0), derived benign and malignant prostatic disease angiographic images and imaging data in terms of difference. Results: 90 patients, 31 patients were diagnosed as malignant, which TRUS-guided biopsy by the number of positive cases was 21 cases, TRCEUS under the guidance of the number of positive cases, 25 cases of which 15 cases were positive for both prompt, TRUS prostate cancer diagnostic sensitivity, specificity, accuracy, positive predictive value, and negative predictive values ??were: 67.7%, 64.4%, 65.6%, 84%, 58.5%, while the TRCEUS were: 80.6%, 93%, 88.9% , 89.3%, 88.7%. 90 patients showed high contrast enhancement, and other enhancements, low enhancement, the number of patients without reinforcement were: 28 cases, 51 cases, 9 cases, 2 cases. Including high enhancement confirmed 25 cases of malignancy, and other enhancements in four cases confirmed as malignant, low Enhancement two cases were malignant, no enhancement 0 cases were malignant. Analysis software obtained using Qontrast all patients angiography imaging parameters, results in benign and malignant lesions parameter differences, which PEAK%, RBV, RBF statistically significant difference. Conclusion: transrectal ultrasonography guided biopsy can improve prostate cancer detection rate, sensitivity and specificity than conventional systems biopsy high, transrectal ultrasound contrast diagnosis of prostate cancer has important diagnostic value. Prostate cancer lesions showed high contrast images are generally perfusion lesion by imaging analysis software, can draw imaging parameters related to the diagnosis of prostate cancer have some help and reference.

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CLC: > Medicine, health > Clinical > Diagnostics > Diagnostic Imaging > Ultrasonic diagnosis
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