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The Regulation of Syndrome-treatment of the Chronic Hepatitis B Liver-Kidney Yin Deficiency Syndrome

Author: GaoZuo
Tutor: SunJianGuang
School: Shandong University of Traditional Chinese Medicine
Course: Chinese medical science
Keywords: Chronic Hepatitis B the syndrome of Liver-Kidney Yin Deficiency treatment law
CLC: R259
Type: Master's thesis
Year: 2011
Downloads: 32
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Abstract


Purpose:Summary of the literature of Chronic Hepatitis B Liver-Kidney Yin Deficiency Syndrome characteristics, and to evaluate the clinical efficacy of Bushenqinggan Fang.Method:Literature over the past decade with Chronic Hepatitis B Liver-Kidney Yin Deficiency Syndrome of the relevant journal literature permit a more comprehensive statistical analysis and summary of the literature, Liver-Kidney Yin Deficiency Syndrome of the standard permit differentiation characteristics and drug law. 60 Hepatitis B patients as research subjects, were randomly divided into two groups. The experimental group (30 cases) was treated with Bushenqinggan Fang, and the control group (30 cases) was treated with specific prescription for certain illness. After 12 weeks’treatment, to observe the patient’s improvements such as: clinical symptom, biochemical indicator, immunity target, virology target, and so on.Results:Documents obtained summary, Chronic Hepatitis B Liver-Kidney Yin Deficiency Syndrome card features to flank pain, five upset hot, weak waist, insomnia, red tongue, dizziness, dry mouth and throat, less moss or no, with two dry is more common. Medication to habitat, wolfberry, angelica, Radix, white peony root is more common, followed by Radix, Radix, Salvia, Ligustrum lucidum, Toosendan, Dan, cornus officinalis, Eclipta prostrata, snake tongue grass, Poria , Once again, yams, giant knotweed, turmeric, Rehmannia, Schisandra, licorice, red peony, Patrina, Radix, Astragalus, Huang Jing.After the treatment of 12 weeks, the total efficiency in the experimental group was 83.33%, which was higher than in the control group 56.67%,which were statistically different (P<0.05).The experimental group and the control group were both statistically significantly different (P<0.01) in improving clinical symptom. In improving the ALT, although the experimental group was higher than the other, which was statistically different(P <0.05). The experimental group was significantly better than the control group, in improving the AST, TBIL, immune parameters, which were statistically significantly different (P<0.01). In the experimental group, negative rate of HBV-DNA was better than the control group, but the two groups have not shown difference ( P>0.05).In the two groups, HBeAg seroconversion rate and HBeAg / HBeAb conversion rate were 0.Anti-virus test group an overall response rate was 67.67%, while the control group response rate was 53.33%. Overall response rate between the two groups, P <0.05, the total response rate of anti-virus of experimental group was better than the control group.Conclusion:Part of literature: the literature of chronic hepatitis B Liver-Kidney Yin Deficiency Syndrome characteristics and features of the pathogenesis of internal heat due to yin deficiency in line with the December 1991 meeting of the development of viral hepatitis in Tianjin TCM (on trial) and Yichang, Hubei Province in May 2004 proposed a "viral syndrome differentiation standard " card in the Liver-Kidney Yin Deficiency Syndrome are the differences in clinical manifestations. Liver-Kidney Yin Deficiency Syndrome drug literature to nourish liver and kidney yin main detoxification supplement, combined.Part of clinical research: with Shuganjianpi.Bushenqinggan Fang has significantly improved symptoms in patients with chronic hepatitis B,resummed their liver function and regulated their immunity. It has certain effet in enhancing anti-viral response rate. And it has not been found the obvious side effect.The treatment method of Bushenqinggan Fang is safe and effective in the clinical applications of Chronic Hepatitis B.

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