|
Objective: To explore the wonderful San flavored with the clinical efficacy of plasmin treatment of acute lower extremity deep vein thrombosis. Method: Select the period from December 2009 to January 2011, 80 cases of hospitalized patients diagnosed with acute deep venous thrombosis, including the onset of 7 days divided into: pure plasmin treatment of 20 cases (A group), three Miao San flavored with the plasminogen in 20 patients (B group), the incidence of 8-28 days divided into: pure plasminogen in 20 patients (C group), the three Miao scattered flavored with the plasminogen in 20 patients (D group). Group A, B, C, D group of patients to establish an observation table, detailed records before treatment and administered 14 days after the symptoms, signs, and laboratory parameters and ultrasound results and alone before treatment, after treatment, 3,7 14 days of D-dimer value for recording. Application SPSS16.0 software was used for statistical analysis. Results: The four groups of patients before and after treatment, symptoms, signs have improved significantly, PT, APTT, FIB and platelet count indicators have varying degrees of change, more significant difference (P lt statistically analyzed in two groups, A, B; 0.05), C, D Comparison of two groups was significant difference (P lt; 0.05). A, B two groups, and C, the D two sets of D-dimer levels before treatment, after treatment, 3,7 days without a significant difference (P gt; 0.05), and 14 days after treatment, a significant difference ( P lt; 0.05). Clinical efficacy: A group, the cure rate is 40%, the total efficiency of 95%; B group, the cure rate was 55%, the total efficiency of 100%; C group, the cure rate is 25%, the total efficiency 85%; D group, the cure rate is 45%, with a total efficiency of 95%; groups A, B two groups and the C, D cure rate was no significant difference (P gt; 0.05). Color Doppler results: group A vein completely recanalization rate was 35%, the total pass rate of 85%; the B groups vein complete recanalization rate was 55%, total pass rate of 95%; C group received intravenous complete recanalization 25%, total pass rate 70%; the D group vein completely recanalization rate of 40% total recanalization was 85%. Two groups B and C, D groups recanalization rate no significant difference (P gt; 0.05). Conclusions: 1. Patients total effective rate of 85%, indicating that plasmin as a new generation of thrombolytic drugs, clinical treatment of acute effect of deep venous thrombosis clear. 2 patients within 7 days duration than patients with duration of 8-28 days, the clinical cure rate and color Doppler recanalization rate. The earlier the better efficacy of treatment of patients with DVT. Part of the clinical symptoms and signs, laboratory tests and ultrasound results after 3 Sanmiao Powder with plasmin treatment compared with plasmin treatment significantly improve the situation, description the three Miao scattered flavored with the the plasmin treatment can significantly improve the clinical efficacy.
|