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Objective: To investigate essential hypertension associated with type 2 diabetes on cardiac structure and left ventricular diastolic function and tissue Doppler imaging (TDI) evaluation of the advantages of left ventricular diastolic function. Methods: The clinical data of hypertension and type 2 diabetes patients hospitalized retrospective study from January 2008 to February 2010, will meet the study criteria were divided into hypertension (EH) group (n = 220), type 2 diabetes mellitus (T2DM) group (n = 63) and hypertension associated with type 2 diabetes (EH T2DM) group (n = 108). The application M mode measurement of left atrial diameter, left ventricular end-diastolic diameter, septal thickness and left ventricular posterior wall thickness, the use of the the Devereux formula for calculation of left ventricular mass index and relative wall thickness, and in accordance with the values ??obtained in patients with left ventricular pattern classification . The application of color flow Doppler measurements the mitral flow the early diastole e peak atrial systolic peak velocity of a peak. Tissue Doppler imaging (TDI) to evaluate myocardial diastolic function by measuring myocardial velocities. Diastolic mitral annular motion along the long axis to of TDI speed mode in the apical four-chamber view, record, and its movement speed is relatively unaffected by the impact of cardiac stress state is the main indicator of the overall evaluation of left ventricular diastolic function. In this study, TDI technology to measure the peak of early diastolic e (e ') and atrial systolic peak velocity (a'), a peak, and the ratio between the two lt; diagnosis of left ventricular diastolic dysfunction standards. At the same time the the SPSS11.5 software on three groups of general information, biochemical markers and ultrasound echocardiography results for statistical analysis and comparison. Results: 1 EH T2DM group age higher than the EH group and T2DM group (p lt; 0.05) lower than the EH group (p lt; 0.05) SBP and DBP, TG below the T2DM group (p lt; 0.01); EH T2DM group, duration of diabetes, SBP and DBP were higher than the T2DM group (p lt; 0.05); the T2DM group TG higher than the EH group (p lt; 0.001), and Cr lower than the EH group (p lt; 0.01). Of 2 EH T2DM group interventricular septum thickness, left ventricular posterior wall thickness, left ventricular mass index and relative wall thickness were higher than the EH group and T2DM group (p lt; 0.01). The EH group left ventricular posterior wall thickness, left ventricular mass index and relative wall thickness were higher than T2DM group (p lt; 0.05). EH T2DM group and EH group left ventricular geometric patterns are mainly concentric hypertrophy, the T2DM group concentric remodeling. Comparison of the three groups of left ventricular geometry the concentric hypertrophy EH T2DM group was significantly higher than the EH group and T2DM group (p lt; 0.001) and lower incidence of normal configuration EH group and T2DM group (p lt; 0.01). The T2DM group normal geometry and concentric remodeling occurred were significantly higher than the EH group (p lt; 0.05), concentric hypertrophy, the incidence was significantly lower than the EH group (p lt; 0.001). E 'of of 3 EH T2DM group was significantly lower than the EH group and T2DM group and left atrial diameter was significantly higher than the EH group and T2DM group (p lt; 0.05). EH T2DM group a 'significantly lower than the T2DM group, while a, e' / a 'higher than the T2DM group (p lt; 0.05). The T2DM group a and a 'lower than the EH group (p lt; 0.05); e / a, e' / a 'higher than the EH group (p lt; 0.05). EH group and EH T2DM group e / a lt; 1 e '/ a' lt; 1 the number of significantly more than the T2DM group (p lt; 0.05). And with e / a ratio make the diagnosis of diastolic dysfunction and there are a lot of \After adjusting for sex, age, smoking, alcohol consumption, hypertension and type 2 diabetes duration, hypertension classification, body mass index, blood pressure, blood lipids, fasting glucose and creatinine, e '/ a' value still with diabetes, left ventricular mass and relative wall thickness (p lt; 0.05) and left ventricular mass index related (p lt; 0.01). Further to the left ventricular diastolic function insufficiency as dependent variables, gender, age, hypertension course of the disease, blood pressure classification, overweight, type 2 diabetes, hyperlipidemia as independent variables, stepwise multiple logistic regression, EH T2DM group occurred left ventricular The diastolic dysfunction risk is of T2DM 1.8 times the risk of EH group is the the T2DM group's 1.4 times. In the EH group, and left ventricular diastolic dysfunction occurred related risk factors for hypertension course of the disease; T2DM group with left ventricular diastolic function insufficiency occurrence of risk factors associated with overweight and hyperlipidemia; in EH T2DM group risk factors associated with left ventricular diastolic dysfunction occurs as blood pressure grades and course of hypertension and overweight. Conclusion: 1 TDI measured mitral annulus velocity is a relative does not rely on the front load evaluation of diastolic function parameters, pseudo-normalization of blood flow can better identify early left ventricular diastolic dysfunction. 2 hypertension, type 2 diabetes greater impact on left ventricular diastolic dysfunction. When hypertension and type 2 diabetes mellitus, make patients with left ventricular hypertrophy and abnormal left ventricular geometry and left ventricular diastolic dysfunction change to maximize the accelerated deterioration of the condition.
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