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Objective: To observe to add enteral nutrition Sijunzitang immune function in critically ill patients , and to explore the Qi Decoction on the application in the clinical treatment of critically ill patients . Methods: A prospective, randomized , single-blind , controlled study , 48 cases of critically ill patients admitted to ICU of our hospital from June 2009 to March 2010 at a 1:1 ratio were randomly divided into a control group and a treatment group were male 27 cases and 21 females , aged 28-73 years old . The control group and the treatment group in Check for ICU24-48 hours , with stable vital signs , homeostasis tends to balance and Enteral Nutrition contraindications nasogastric full enteral nutrition support , treatment group injected by stomach tube Sijunzitang 200m1, the course of one week . Check the ICU24 hours and after the end of treatment was extracted from peripheral venous blood , detection of T lymphocyte subsets (CD4, CD3, CD4 / CD8), NK cell activity , immunoglobulin (IgA , IgM , IgG ), and recorded during the study period group enteral nutrition in patients intolerant to common gastrointestinal complications (gastric retention , nausea and vomiting , aspiration , bloating, diarrhea) , pulmonary fungal infection and MODS . Measurement data to x ± s , between the two groups with the t test , count data using the X2 test , P lt ; 0.05 as statistically significant . All statistics were used SPSS17.0 statistical software . Results: 41 patients completed the study , the treatment group, 21 cases , 20 cases of the control group . The gender composition of the study before the treatment group and the control group than , age of APACHE II score were no statistically significant differences between the treatment group and the control group as measured by CD4 , CD3 , CD4 / CD8 , NK cell activity , IgM, IgG , IgA are in the low state . After one week of treatment , the study group and the treatment group, CD4 , CD3 , CD4 / CD8 , NK cell activity and IgM , IgG , IgA, were significantly improved, while the treatment group was significantly higher than that of the control group ( P lt; 0.05 ) . Enteral nutrition intolerance gastrointestinal complications (gastric retention , nausea and vomiting , aspiration , bloating , diarrhea ) the incidence of treatment group than the control group , the treatment of pulmonary fungal infection rates and incidence of MODS lower than control group. Conclusion : the auxiliary Sijunzitang enteral nutrition support in critically ill patients can further improve immune function , optimize enteral nutrition support effects and improve the tolerability of early enteral nutrition , reduce the incidence of pulmonary fungal infection and MODS .
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