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The community population distribution characteristics of the purpose of the first part of the Beijing the community crowd coronary calcification preliminary evaluation of coronary artery calcification (coronary artery calcium distribution CAC) and coronary artery calcification score (coronary artery calcium score, CACS), for the introduction of coronary calcification the prevention and treatment of people with coronary heart disease risk stratification assessment and provide baseline data on the the coronary calcification evolution research. Materials and methods to develop the inclusion and exclusion criteria, random sample of Beijing Shougang, Shijingshan and the Xishan three communities in population-based case-Radiology, Fuwai Hospital from September 2007 to January 2010, the use of 64-MDCT (GE LightSpeed ??VCT) of coronary artery calcification scanning the crowd, application Agatston integration method to calculate the coronary artery calcium score, observed CAC and CACS distribution characteristics to CAC and CACS difference in gender and age group were compared between groups. 1) a total of 2507 cases of objects selected, age 53.68 ± 8.68 years old, male, a total of 1188 cases (47.4%), a total of 843 cases found that CAC (positive rate of 33.6% total sample). Male CAC positive rate was 41.3% (491/1188), was significantly higher than that of women 26.7% (352/1319) (p lt; 0.001). 2) total sample, the same gender, the same gender within each age group CACS were positively skewed distribution. CAC positive rate in the same gender and CACS increased with age and was significantly higher (p lt; 0.01); addition to ≤ 40 years of age and gt; 70-year-old group, the CAC positive rate of men in each age group and CACS than in the female group high ( p lt; 0.001). 3) All subjects in 363 cases (14.5%) for single vessel calcification, 480 cases (19.2%) is more than just calcification, no significant difference between the sexes. 4) 2507 cases of the total sample left main, left anterior descending artery, the circumflex artery and the right coronary artery, coronary calcification incidence before descending coronary artery (747 cases, 29.8%) and right coronary artery (407 cases, 16.2%) The high incidence rate (p lt; 0.001), coronary calcification significant difference between the rate of sex, men calcification were higher than females (p lt; 0.001). Conclusion community population of coronary artery calcification situation there are significant differences between gender and age. 64-MDCT can conveniently and quickly quantify to detect community population CAC CAC evaluation population distribution characteristics and laws of preliminary determination crowd coronary atherosclerotic lesions. The correlation between the second part of the Beijing community population of traditional risk factors of coronary artery calcification and coronary heart disease research purposes to evaluate the correlation between coronary artery calcification of community population with traditional coronary heart disease risk factors. Materials and methods to develop the inclusion and exclusion criteria, random sampling Beijing Shougang, Shijingshan, Xishan community population of 1863 cases, Radiology, Fuwai Hospital from May 2008 to January 2010, the use of 64-MDCT (GE, the LightSpeed ??VCT ) coronary calcification scan the crowd, application Agatston integration method to calculate the coronary artery calcium score, and selected cases for investigation of coronary heart disease risk factors and clinical ECG, blood pressure, blood biochemical examination. Grouped by gender, the correlation between the two Logistic regression analysis and evaluation of CAC and risk factors as dependent variables to CAC, CACS natural logarithmic transformation [1n (CACS) 1n (CACS 1) multiple linear the correlation between the regression evaluation CACS risk factors. Results 1863 cases Subjects ranged in age from 35 to 77 years (mean age 54.09 ± 8.61 years), male 887 cases (47.6%). Male CAC positive rate in women (43.2% and 29.0%, p lt; O.001) men CACS score higher than women (111.91 ± 318.46 and 58.09 ± 222.69, respectively, p lt; 0.001). The male CAC CACS independent risk factor for age, hypertension, diabetes and coronary heart disease, a family history (p lt; 0.05); occurrence of women CAC and CACS independent risk factor for age, hypertension and hyperlipidemia ( p lt; 0.05). After adjustment for gender, the CAC independent risk factors were age, hypertension, hyperlipidemia, diabetes, and family history of CAD (p lt; 0.05); CACS independent risk factor for age, hypertension, diabetes and coronary heart disease family history (p lt; 0.05). Conclusion MDCT found the community crowd coronary calcification and its degree of traditional cardiovascular disease risk factors are related. Assessment of traditional risk factors, we can predict the existence and extent of the crowd coronary atherosclerosis. Traditional cardiovascular risk factors, hypertension and diabetes on the best age on coronary atherosclerosis progression predicted the best prediction of coronary atherosclerosis occurred. The third part of the the Beijing Xishan community crowd carotid artery intima-media thickness and coronary artery calcification Objective To evaluate the distribution of the the Beijing Xishan community crowd carotid intima-media thickness (inter-media thickness, IMT) and the crowd coronal artery calcification (coronary artery calcium, CAC) correlation. Materials and methods sampling the Beijing Xishan community population of 1205 cases, carotid ultrasound detected bilateral common carotid artery (common carotid artery, CCA) intima-media thickness of the carotid artery (internal carotid artery, ICA). And 64-MDCT for coronary calcification scan the crowd, the application Agatston integral method of coronary artery calcification score (coronary artery calcium score CACS) were calculated, and observation of the CCA-IMT and ICA-IMT presence or absence of gender, age, CAC CACS grouping (0,0 to 100, 101 to 400, 401 to 1000 gt; 1000) when the distribution of characteristics and CCA-IMT, ICA-IMT and CACS correlation. The results of 982 patients were enrolled, aged 35 to 75 years (average age 54.26 ± 9.92 years), 475 cases of male. Men CCA-IMT and ICA-IMT were higher than women (respectively: O.86 ± 0.19 vs 0.80 ± 0.17, p lt; 0.001; 0.65 ± 0.15 vs 0.60 ± 0.14, p lt; 0.001), CAC positive rate and CACS Yiyi men than in women (p lt; 0.001). CAC positive (the CACS gt; 0) when no significant gender difference (p = 0.29), CACS. Gender within each age group between CCA-IMT and ICA-IMT increased with age (p lt; 0.001) increase. CCA-IMT gender CAC positive and negative ICA-IMT compared with CCA CCA-IMT and ICA-IMT thickness (p lt; 0.001). In addition to the group of 101 to 400 men and women CACS integral ICA-IMT and women CACS integral group of 401 to 1000 CCA-IMT, gender CACS higher group CCA-IMT and ICA-IMT higher (p lt; 0.001) . Spearman correlation analysis showed that gender within CACS with CCA-IMT, ICA-IMT there are mild positive correlation (CCA-IMT correlation coefficients were 0.35 and 0.41; ICA-IMT correlation coefficients were 0.30 and 0.26 ) (p lt; 0.001). Conclusion community population grouped by gender, age, CAC-positive rate and CACS carotid artery carotid artery intima-media thickness between the existence of group differences. Carotid artery, carotid artery intima-media thickness with CACS mild positive correlation between both subclinical coronary atherosclerosis remains to be further studied.
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