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Study on the Clinical Value of Serum Myocardial Enzymes in Children’s Obstructive Sleep Apnea Hypopnea Syndrome

Author: WangYin
Tutor: WangBinQuan
School: Shanxi Medical
Course: Department of Otolaryngology,
Keywords: Obstructive sleep apnea -hypopnea syndrome Child Polysomnography Myocardial enzymes
CLC: R766
Type: Master's thesis
Year: 2010
Downloads: 46
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Abstract


Objective: To understand the obstructive sleep apnea hypopnea syndrome ( obstructive sleep of apnea to hypopnea syndrome OSAHS ) changes in the levels of serum myocardial enzymes , to determine the impact of children OSAHS myocardial damage ; study OSAHS preoperative and postoperative serum enzyme changes of the spectrum , to determine the role of surgical treatment of OSAHS in children , provide some theoretical basis for the prevention and protection of children OSAHS complications treatment . Methods : 1 . Collect 90 cases of child patients with OSAHS , light , severe 30 cases where children admitted to hospital with severe OSAHS adenoidectomy and / or tonsillectomy , 60 cases of postoperative January follow-up children , child protection examination 30 cases of normal children as a control group , OSAHS children underwent polysomnography sleep monitoring ( polysomnogruphy PSG) . 2 . Collected fasting serum of the above cases , automatic biochemical analyzer and compare groups between myocardial enzymes levels . 3 . Use of statistical methods to analyze serum myocardial enzymes OSAHS children during sleep apnea hypopnea index ( of apnea to hypopnea index , AHI) and lowest oxygen saturation ( lowest oxygen saturations relationship between LSaO2) and their correlation . Results : 1.PSG results : children with OSAHS severe group , postoperative AHI and LSaO2 of preoperative comparison, the differences were statistically significant ( respectively P lt ; 0.05 , P lt ; 0.05) . 2 myocardial enzymes of light in the severe group OSAHS patients compared with normal control group was significantly increased, and the difference was statistically significant ( P lt; 0.05 ) . 3 . The severe group OSAHS postoperatively in January compared with the preoperative myocardial enzymes level significantly lower , the difference was statistically significant ( P lt; 0.05 ) ; severe group OSAHS than the normal control group, postoperative myocardial enzymes levels were not significantly changes , the difference was not statistically significant (P gt; 0.05). Children OSAHS patients with serum myocardial enzymes with AHI increase and hypoxia severity increased with AHI positively related ( P lt ; 0.05 ;) . Related LSaO2 negative (P lt; 0.05). Conclusion : 1.OSAHS children sleep hypoxemia and acidosis repeated episodes of myocardial damage . With increasing degree of OSAHS children hypoxia , myocardial injury may be heavier . 3 . Surgery to unblock as an effective way of treating children OSAHS .

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