Dissertation > Excellent graduate degree dissertation topics show

Study on the Change of Red Blood Cell in Patients with Obstructive Sleep Apnea-Hypopnea Syndrome after Operation

Author: LiLiMin
Tutor: ShangXiaoLing
School: Hebei North University
Course: Pathology and Pathophysiology
Keywords: Obstructive sleep apnea hypopnea syndrome Modified-coblation assisted uvulopalatopharyngoplasty Red blood cell Polysomnography Apnea-hypopnea index Oxygen saturation
CLC: R766
Type: Master's thesis
Year: 2013
Downloads: 6
Quote: 0
Read: Download Dissertation

Abstract


Obstructive sleep apnea-hypopnea syndrome (OSAHS) is a common disease in clinic, which seriously affect the quality of the life and the health of the patients. In this study the change of red blood cell in patients withOSAHS after modified-coblation assisted uvulopalatopharyngoplasty (UPPP) was observed to clarify the correlation between red blood cell and severity of disease in patients with OSAHS and the significance of red blood cell in the clinical prognosis in patients with OSAHS after modified-coblation assisted UPPP.50patients with OSHAS, who visited the otolaryngological department of our hospital from March2011to August2012, were included in this study. Polysomnography(PSG) Monitor was carried, and red blood cell count (RBC), hemoglobin (HGB), and hematocrit(HCT) were determined before and after modified-coblation assisted UPPP.50healthy subjects who took the physical examination in the same term were included into Control Group. PSG Monitor was carried, and RBC, HGB, and HCT were determined in50healthy subjects in the same methods. The difference of RBC, HGB and HCT among patients with OSAHS and healthy subjects was analyzed. The correlation between severities of disease and levels of RBC, HGB, and HCT before operation in patients with OSAHS was analyzed. The difference of RBC, HGB and HCT before and after operation was analyzed. The correlation between severities of disease and levels of RBC,HGB, and HCT before operation in patients with OSAHS was analyzed.We can get the results that (1) The age and gender of the patients with OSAHS and healthy subjects were not significantly different(P>0.05), and there were15cases with mild OSAHS,24cases with moderate OSAHS and severe OSAHS,7cases with hypertension and11cases with type2diabetes mellitus in50patients with OSAHS.(2) The levels of RBC, HGB and HCT were significantly higher than those of healthy subjects (P<0.01).(3) The levels of RBC, HGB and HCT before operation were positively correlated to apnea-hypopnea index (AHI) before operation (P<0.01); the levels of RBC, HGB and HCT before operation were negatively correlated to Oxygen saturation (SaO2) before operation (P<0.01).(4) The levels of AHI, RBC, HGB and HCT in6th month after operation were significantly decreased compared with those before operation (P<0.01), but the level of SaO2in6th month after operation was significantly decreased compared with that before operation (P<0.01).(5) The level of RBC before was positively correlated to apnea-hypopnea index (AHI) after operation (P<0.01), and the levels of RBC, HGB and HCT before were negatively correlated to Oxygen saturation (SaO2) after operation (P<0.01).The conclusions are (1) The levels of RBC, HGB and HCT increase in patients with OSAHS, and are related to the severity of disease.(2) Modified-coblation assisted UPPP can improve the AHI and the lowest SaO2, and decrease the levels of RBC, HGB and HCT in patients with OSAHS;(3) The levels of the levels of RBC, HGB and HCT before and after operation are correlated to the efficacy of modified-coblation assisted UPPP.

Related Dissertations

  1. Sleep Architecture in Acute Stroke and Correlation Factor,R743.33
  2. A Snoring Detector for OSAHS Based on Formant,R766
  3. The Level of Serum Apelin and Its Correlation with Lipid Metabolism and Insulin Resistance in OSAHS Patients,R766
  4. Animals developed pulse oximetry components,S854.9
  5. Application of Photoacoustic Microscopy in Cerebral Hypoperfusion Model of Rats,R743.3
  6. MSP430-based human signal detection and alarm system,TN911.23
  7. A Study into the Polysomnogram of Parkinson’s Disease and the Efficacy of Sinemet on Parkinson’s Disease with Sleep Disorder,R742.5
  8. Study on Non-invasive Pulse Monitor of Oxygen Saturation of Blood,TH776
  9. Plasma Adrenomedullin in Relevant to Obstructive Sleep Apnea-hypopnea Syndrome and Hypertension,R544.1
  10. The Clinical Research of Syndrome Law of Hypoxemia Secondary to Virus B Hepatitis and Its Pathogenesis,R259
  11. Precision Sigma-Delta ADC based on the oximeter Research and Implementation,TN792;TP216
  12. Development of a Portable Instrument for Monitoring Physiological Parameters During Physical Exercise,R318.6
  13. 138 cases of Victoria , Han ethnic female snorers polysomnography index difference comparative analysis,R766
  14. The Study of Cognitive Fuction, Sleep Structure and Diurnal Blood Pressure in Stoke Combined with Obstructive Sleep Apneah Hypopnea Syndrome,R743.3
  15. Changes of Leptin and Blood Lipid in Patients with Obstructive Sleep Apnea-hypopnea Syndrome before and after Operation,R766
  16. Macrostructure of Sleep in Patients with Vascular Cognitive Impairment-no Dementia,R749.1
  17. The Related Factors of "Epileptiform Discharge" in PSG in Idiopathic Epilepsy,R742.1
  18. Hypoxemia Secondary to Hepatitis B-related Syndromes an Clinical Research Indicators,R259
  19. Detection of Pulse Oxygen Saturation in Strong Noise Background,R131
  20. Nocturnal Sleep Determinants for Excessive Daytime Sleepiness in Obstructive Sleep Apnea Syndrome,R766.43
  21. Investigate the Correlation between the Epworth Sleepiness Scale and PSG in Diagnosis of Obstructive Sleep Apnea-Hypopnea Syndrome,R766

CLC: > Medicine, health > Otorhinolaryngology > To pharynx Science, pharyngeal disease
© 2012 www.DissertationTopic.Net  Mobile