|
The dermatofibrosarcoma protuberans sarcoma (DFSP) Objective To analyze the influence of the main factors of the invasive growth range, about the DFSP growth range with many influencing factors of the multiple linear regression model to explore the range of quantitative methods to determine tumor surgical resection estimate a few cases the the extent of surgical resection of the tumor. Methods of Anhui Medical University First Affiliated Hospital of Anhui Provincial General Hospital DFSP confirmed cases from 2001 to 2009 a total of 63 cases, the cases divided by number of incidence initial cases and recurrent cases analyzed retrospectively DFSP recurrence related influencing factors; 11 new cases in 63 cases the tumor location into the trunk and head and neck, the use of the stereological principle in accordance with 1.5 points, 3.0 points, 4.5 points, 6.0 points, 7.5 points, 9.0, 10.5 points to 12.0 points, the positioning of the tumor tissue samples respectively with the skin in the Members longitudinally drawn, the absolute value of the measurement variable using computer image analysis system, the combination of statistical methods to create two groups of tumor-infiltrating growth range (D) and tumor the radius (R), age (age) and gender (sex) variable multiple linear regression model. Use of mathematical models to estimate the extent of resection of the tumor in the individual case. Results of the factors affecting the DFSP recurrence of tumor size, growth site, tumor depth, frequency and incidence of surgical resection of the range; variables associated with DFSP invasive growth range of tumor size, tumor depth, growth site, frequency and incidence of tumors organizations edge pseudopodia / horizontal length of the honeycomb structure, the edge of pseudopodia / depth of the honeycomb structure; tumor size was included in the multiple regression model, patient gender, age as balancing variables included in the multiple regression model, the establishment of the trunk and the head different parts of the neck tumor regression equation dip growth range, two sets of multiple regression models were statistically significant (P lt; 0.05). Head and neck D1 = 0.1746 0.1404R-1.9351sex 3.0754age1, the coefficient of determination of the equation 0.65, the adjustment coefficient of determination of 0.54, better model fit, the radius of tumor regression coefficient was 0.14 (P = 0.001), a statistically significance; the trunk regression equation in the radius of the tumor regression coefficients of -0.01 (P = 0.784) was not statistically significant. Conclusion The analysis of the different parts of dermatofibrosarcoma fibrosarcoma, the main factors to affect the range of the invasive growth of the tumor tumor size, tumor depth, growth area, the number of incidence, tumor tissue edge pseudopodia / honeycomb structure The horizontal length of the edge pseudopodia / depth of the honeycomb structure. To establish a mathematical model on the head and neck DFSP growth range relative to the tumor size, age and sex. And less than the 40-year-old male in the growth of the head and neck DFSP to predict when the maximum tumor diameter to 1.0cm, 2.0cm, 3.0cm tumor resection can not be less than 0.8cm, 1.5cm, 3.1cm.
|