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Objective: In this study, back pain and spinal arthritis survey by the Beijing Capital Iron and Steel Company workers, combined with pelvic plain films and HLA-B27 detection calculated Shougang Company workers for axial spondyloarthritis (SpA) suffering morbidity, a rough estimate of the prevalence of axial SpA in Beijing and the surrounding areas, and verify the the ASAS classification standards is available for the diagnosis of axial SpA. Methods: A cluster random sampling method from a subsidiary of Shougang Company 50 units and departments, randomly selected 34 units staff a total of 15,357 people for the survey questionnaire, followed by three rheumatology specialists to analyze the questionnaires and suspected inflammatory low back pain (IBP), the SpA family history of psoriasis, iritis staff face-to-face interrogation, physical examination, and highly suspicious for axial SpA staff pelvic X-ray examination and PCR methods detection of HLA-B27, the last comprehensive evaluation of results obtained for axial SpA, in accordance with the 2009 International spondyloarthritis Evaluation Association (ASAS) classification criteria for axial SpA diagnosis consists of 2 groups of 6 rheumatologists its The prevalence of subtypes, the 2005 national census data standardization results. Results: (1) issued a total of 15,357 questionnaires were 12125 copies of questionnaires, which suspected the IBP, family history of psoriasis, iritis 731 face-to-face interrogation and physical examination, high index of suspicion for axial SpA pelvic X-ray, and HLA-B27 Check 138, the last comprehensive evaluation to determine axial SpA for 68 people (46 men and 22 women), including AS a maximum of 38 (55.9%), followed by uSpA, 21 (30.9%), followed by PsA 6 (8.8%), the IBDA 2 people (2.9%), ReA 1 (1.5%). (2) The age and sex standardized estimated prevalence of axial SpA was 0.577% (95% confidence interval, 0.442 to 0.712), the AS prevalence was 0.361% (95% confidence interval, 0.254-0.468) . Male incidence was significantly lower than in the axial SpA women (0.511% VS 0.851%), while in the AS, males accounted obvious advantages (0.385%-VS 0.283%). (3) during the check 138 out of 65 cases of sacroiliitis, of which the Bilateral II below the rank of 27 cases, bilateral grade Ⅱ 18 cases, bilateral Ⅲ grade nine cases, seven cases of bilateral Ⅳ grade, unilateral 4 cases of grade Ⅲ. 64 all axial SpA in HLA-B27 positive, the positive rate of 94.1%, 74 people in diagnosis of axial SpA, HLA-B27 positive, the positive rate was 10.8%, both compare HLA-B27-positive rate is a statistically significant difference (P lt; 0.01). (4) The prevalence of different age groups of the same, with the highest prevalence of the 17-29 year-old age group, the prevalence decreased with increasing age, the prevalence decreased significantly over the age of 40. In the age of onset and HLA-B27-positive rate, no significant difference between men and women (93.5% VS 95.5%, P gt; 0.05) in the sacroiliac joint radiographic changes in men was significantly higher than women (69.6% VS 27.3 %, P lt; 0.01) (5) of all patients examined to verify and found that the the Amor criteria of sensitivity and specificity were 82.3% and 80.0%, ESSG standard of 77.9% and 84.3%, respectively. Conclusion: (1) the epidemiological investigation of new applications on SpA questionnaire suitable for China to carry out the screening of the central axis SpA. Shougang Company workers axial SpA prevalence is higher for axial SpA after sex and age-standardized prevalence rate of 0.577%, once past our survey results slightly low. AS is the most subtypes followed for uSpA, PsA, IBDA and ReA. (2) with the previously reported dominant SpA and AS men compared the survey found that men in the AS population slightly dominant in the entire axial SpA, the male prevalence is significantly lower than the female, to consider may be due to the female symptoms than men to light, and the rate of progress of the X-ray to be significantly lower than that of men, the rate of clinical treatment and diagnosis rate due to lower than males. Axial SpA and AS prevalence in adults has obvious age difference, the highest prevalence in the age between 20-30 years old. (3) IBP as axial SpA The most common symptoms and important feature of the diagnosis of axial SpA is still not comprehensive, this study showed that only 56.9% of the total number of IBP IBP for axial SpA, and therefore still need to combine other clinical features or laboratory tests to the final diagnosis of axial SpA. (4) According to the the ASAS classification standard diagnosis of axial SpA the validation Amor criteria and ESSG standard, found the ASAS classification criteria, Amor standards and ESSG standard diagnostic classification can be used in China's central axis SpA.
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