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Objective: hypertensive heart disease and electrocardiogram (ECG) showed left ventricular hypertrophy (LVH) associated with strain plasma B-type natriuretic peptide (BNP), the determination of relevant factors and clinical significance. Method: August 2008 to March 2010, 68 cases by echocardiography Figure diagnosed hypertensive heart disease patients, including 40 males, 28 females, mean age 64.5 ± 11.7 years, according to the ECG of LVH accompanied strain were divided into two groups, Ⅰ (LVH with strain) and group Ⅱ (LVH associated with strain) BNP determination of the two groups of patients, while on the course of hypertension, blood pressure levels, including 24-hour ambulatory blood pressure as well as symptoms, physical and chemical indicators were observed on the part of the patients underwent coronary angiography, SPSS11.5 software for statistical analysis of the observational data. Results: ① patients with hypertensive heart disease ECG was LVH partners strain change detection rate of 38.2%: of 2 BNP measured value I group to 57.60 ± 18.70 pg / ml, Ⅱ group was 17.20 ± 2.52 pg / ml, differences statistically significant significance (P = 0.009 lt; 0.05); ③ The group Ⅰ a history of hypertension, an average of 13.31 ± 11.21 years, Ⅱ group average of 12.76 ± 12.26 years, the difference was not statistically significant (P = 0.854 gt; 0.05) I group of patients on admission contraction pressure 170.19 ± 26.70mmHg, diastolic blood pressure 91.54 ± 15.41mmHg Ⅱ group systolic blood pressure 157.26 ± 21.84mmHg diastolic pressure 91.67 ± 10.52mmHg, systolic blood pressure differences between the two groups was statistically significant (P = 0.033 lt; 0.05); ④ 24-hour ambulatory blood pressure monitoring results are non-dipper blood pressure detection rate of 70.6%, the Ⅰ group of 23 cases, accounting for 88.5%, group II 25 cases, accounting for 52.1%, the difference between the two groups have a significant statistical difference (P = 0.023 lt; 0.05 ). The group Ⅰ patients with nocturnal blood pressure decline to 5.8 ± 4.5%, II group nighttime blood pressure decreased 7.4 ± 3.0%, the difference was statistically significant (P = 0.027 lt; 0.05); ⑤ symptoms of chest tightness and chest pain 20 group I cases, accounting for 76.9%, Ⅱ group of 16 cases, accounting for 38.1%, the difference was statistically significant (P = 0.040 lt; 0.05), paroxysmal nocturnal sleep breathing difficulties I group, 18 patients accounted for 69.2% of group II patients (21.4%), the difference was statistically significant (P = 0.000 lt; 0.05); ⑥ A total of 33 patients who underwent coronary angiography in the two groups of patients in group Ⅰ 19 cases, accounting for 73.0%, Ⅱ 14 cases, accounting for 33.3% slow flow phenomenon I 9 cases, accounting for 47.4%, group II cases, accounting for 7.1% of the difference between the two groups was statistically significant (P = 0.036 lt; 0.05). Conclusion: ① hypertensive heart disease ECG showed LVH associated with the strain serum BNP was significantly higher than that of hypertensive heart disease ECG associated with strain in patients without LVH; ② of BNP increase reflects hypertensive heart disease and ECG showed LVH partners strain may be present in patients with more severe diastolic dysfunction, microcirculatory dysfunction may be hypertensive heart disease ECG was one of the main reason for the worsening of LVH associated with strain in patients with diastolic dysfunction; ③ long-term systolic blood pressure increased, the physical laws of the nighttime blood pressure disappears microcirculation dysfunction may be the main reason of hypertensive heart disease ECG showed LVH associated with strain; the ④ reduce blood pressure and restore the physical laws of the nighttime blood pressure may help prevent the occurrence or prevention of ECG LVH LVH accompanied strain change, and by improving the micro- The circulatory function improve diastolic function, thereby improving the long-term prognosis of patients.
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