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The risk factors for the purpose of understanding our hospital Stenotrophomonas maltophilia (Stenotrophomonas maltophilia, SMA) Aeromonas resistance to respiratory infections, the clinical significance of the to affect respiratory infection outcome in SMA patients. The method of determination of the 65 SMA isolated in May 2009 - March 2010 four antimicrobial agents minocycline, sulfamethoxazole, levofloxacin, imipenem sensitivity and resistance analysis. Collection of which 33 cases of respiratory tract infection SMA patient's gender, age, underlying diseases, hospitalization days, separating the SMA before the hospitalization time, indwelling catheter types and the number of mixed infection of the situation as well as antibacterial drug situation, and patients admitted to hospital, other bacteria (in addition to SMA) positive culture the SMA cultivate positive first day's body temperature, blood pressure, respiratory rate, pulse, blood count, liver function, blood gas analysis, APACHE Ⅱ score (Acute Physiology and Chronic Health Evaluation Ⅱ, acute physiology and chronic health evaluation Ⅱ ). Using t-test and Spearman correlation analysis to understand the clinical significance and outcome factors SMA infection. Results 33 cases of respiratory infections SMA patients, 25 males and 8 females; average length of stay was 40.41 ± 27.88 days, cultivate the average length of stay in front of the SMA is 24.41 ± 15.51 days. The average age was 65.24 ± 18.81 years, 26 cases (78.78%) ≥ 60 years of age. Underlying diseases, blood diseases accounted for 10 cases (30.30%); malignant tumors in 8 cases (24.24%); chronic disease in 9 cases (27.27%), three of a total of 81.81%. All patients had deep venous catheter, catheter diverse, including 13 cases (39.39%) patients with left gastric tube, left ureter in 11 cases (33.33%), 10 cases (30.30%), central venous catheter, 9 cases (27.27%) of the trachea was intubated assisted ventilation. 33 patients with fungal infection in 19 cases (57.58%), Acinetobacter baumannii, 18 cases (54.55%), Pseudomonas aeruginosa in 16 cases (48.48%), Enterobacter cloacae, 12 cases (36.36%), methicillin-resistant 8 cases (24.24%) of coagulase-negative staphylococci. The SMA before infection, 27 patients (81.82%) use plus enzyme inhibitors antibiotics, use of hydrocarbon enzyme Greek class of antibiotics in 24 cases (72.73%), 20 cases (60.61%) of the anti-fungal treatment, 10 cases (30.30 %) linezolid use of quinolones in 9 cases (27.27%). Outcome: cured three cases (9.09%), effective in 11 cases (33.33%), progressive cases (3.03%), ineffective in 18 cases (54.55%). Patients admitted to hospital, other bacteria (in addition to SMA) positive culture, SMA culture positive first-day APACHE Ⅱ scores were 16.34 ± 5.07,18.96 ± 5.36,19.8 ± 6.62 * twenty-two the t-test, only the first day of hospitalization and APACHE Ⅱ score SMA positive culture first day there is a statistically significant difference (P lt; 0.05). APACHE Ⅱ score ≥ 15 points in the first day of the patients admitted to hospital, 22 cases, 12 cases (71.43%). The first day of admission APACHE Ⅱ score and outcome of both correlation, correlation coefficient 0.382 * (P lt; 0.05). 65 SMA susceptibility results for: minocycline, co-trimoxazole, levofloxacin, imipenem resistance rates were 10.77%, 13.85%, 32.31%, and 100% Conclusion ① long hospital stay; older ; critical underlying disease; catheter indwelling; presence of mixed infections, the use of a large number of high-grade antibiotics; APACHE II score gt; 15 points may be a risk factor for respiratory tract infection SMA. ② APACHE Ⅱ score the higher the score, the respiratory tract infection SMA higher mortality. ③ respiratory SMA positive culture may prompt patients sicker. ④ our hospital clinical Stenotrophomonas narrow food Aeromonas bacteria and minocycline, cotrimoxazole can be the first choice for empirical treatment.
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