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The new insecticidal activity of the lead compound synthesis, crystal structure , and the insecticidal activity of
Author: LiXueFei
Tutor: XueSiJia
School: Shanghai Normal University
Course: Organic Chemistry
Keywords: N-benzyl - α , α - diphenyl-2 - pyrrolidinemethanol Ultrasonic radiation Insect growth regulator Hydrazide Synthesis Crystal structure
CLC: S482.3
Type: Master's thesis
Year: 2008
Downloads: 96
Quote: 0
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Abstract
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In order to find a novel insecticidal activity found the 21st century pesticide development requirements lead compound completes the synthesis of the two series of compounds : (1) In anhydrous anaerobic , ultrasonic radiation , the N-substituted benzyl proline benzyl yl ester with a substituted phenyl magnesium bromide was synthesized from 9 not been reported in the literature of N-benzyl -alpha , alpha - diphenyl-2 - pyrrolidinemethanol derivative the (Ia ~~ II ) . The N'-substituted- phenoxy acetyl -N- furoyl hydrazide derivative ( IIa to IIg ) , (2) substituted phenyl furoyl chloride with a substituted phenoxy acetyl hydrazine to give 7 not been reported in the literature . Target compound ( Ia to Ii) , (IIa ~~ IIg ) formula as follows : elemental analysis , infrared spectroscopy , NMR , MS , and structural characterization of the two series of compounds , and their physical the nature of the spectral properties of the reaction conditions , the synthesis method for the systematic analysis and discussion . In order to further understand the structure of the compound , N-benzyl - alpha , alpha- diphenyl-2 - pyrrolidinemethanol derivative (Ih) and ( ii ) single crystal culture , determination of the crystal structure , and conducted a preliminary the structure-activity relationship analysis . Pharmacodynamic Ministry of the two series were insecticidal activity screening results show that the series (Ia ~ Ii) good insecticidal activity series commissioned by the Academy of Agricultural Sciences , Shanghai Institute of Plant Protection and National Southern Pesticide Research and Development Center ( Shanghai ) (IIa ~ IIg) compounds have a certain amount of insecticidal activity .
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CLC: > Agricultural Sciences > Plant Protection > Pesticide ( chemical control ) > Various pesticides > Pesticides
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