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Relationship between Peripheral Augmentation Index and Central Augmentation Index

Author: HaoJie
Tutor: DuJun;CuiZuo
School: Hebei Medical University
Course: Internal Medicine
Keywords: Arterial stiffness Reflected wave augmentation index Central aortic Peripheral arterial Coronary heart disease
CLC: R443
Type: Master's thesis
Year: 2008
Downloads: 78
Quote: 0
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Abstract


Objective To investigate the central artery and peripheral arterial reflected wave enhancement index (augmentation index, AI) for peripheral arterial AI reflects how well the central artery of AI. Explore by peripheral arterial measuring central aortic AI method is consistent with direct measurement of central aortic AI. Methods studied 60 consecutive patients in our hospital, parallel coronary angiography, coronary angiography during surgery in December 2007 to March 2008 were collected to the the aortic (Center artery) at the radial pulse pressure waveform diagram artery at two parts of the upper section (outer peripheral arteries), calculated based on the pressure waveform diagram showing the two of the reflected wave augmentation index (Augmentation Index, AI). Radial artery segment at the AIr formula for the AIr = P2/P1, where P1 by the peripheral vertex to wave back peripheral integration to the heart of the reflected wave formed by the fusion wave, P2 LVEF return to the heart the vertices of the reflected wave; central artery i.e. at the aorta Aia = (Ps-Pi) / (Ps - Pd), where Ps is the forward wave and the reflected waves generated by the vertices of the fusion wave Pi systolic and reflected waves before wave encounter the reflection point, Pd is the minimum value of the pressure wave diastolic blood pressure values. 3 AI value calculated and averaged using a continuous three pulse waveform diagram of the calculation of the two AI. Results (1) peripheral artery (radial artery segment at) with the central artery (aorta) AI was positively correlated, r = 0.746 (P lt; 0.01). (2) peripheral arterial and central aortic AI regression equation: y = 10.17 0.56x (where y represents the central aortic AI x representatives peripheral arterial AI). Central aortic AI through peripheral arterial speculated the direct measurement of central aortic AI by paired t-test showed no statistically significant difference (p gt; 0.05). (3) Multivariate logistic regression analysis showed that the age of the exclusion of this group, systolic blood pressure, diastolic blood pressure, pulse pressure, and other factors, the central aortic AI independent risk factor for coronary heart disease (OR = 1.074,95% confidence interval 1.021 ~ 1.129, p lt; 0.01). Conclusion (1) AI and central aortic AI peripheral arterial good correlation. (2) the use of peripheral arterial AI speculated that central aortic AI and direct measurement of central aortic AI two methods have consistency. By measurement of peripheral arterial access reliable central aortic augmentation index. (3) the central aortic AI is an independent risk factor for coronary heart disease.

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