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Objective: 1. Analysis of plasma N-terminal pro-B-type natriuretic peptide (NT-proBNP) concentration and cardiac functional class (NYHA classification), left ventricular ejection fraction (LVEF), left ventricular systolic diameter (LVESD), left The relationship between ventricular end-diastolic diameter (LVEDD), NT-proBNP to study the evaluation of cardiac function. Conventional western medicine treatment and in Western medicine combined with the differences in efficacy of treatment, to explore the Kangda YiXin plasma NT-proBNP concentration intervention and treatment of CHF mechanism. Methods: 60 patients diagnosed with heart failure (CHF) outpatient or hospitalized patients, 30 healthy subjects were selected as the normal control group; CHF diagnosis based on history, symptoms, signs, and objective examination clinicians make comprehensive judgments gold standard, according to the New York Heart Association (New York Heart Association, NYHA) heart function grading program in patients with heart failure, cardiac functional grading; plasma NT-proBNP concentration was measured by enzyme-linked immunosorbent assay (ELISA), echocardiography Figure determination of LVEF, LVESD and LVEDD. 2. NYHA class II CHF patients to Ⅳ grade were randomly divided into the western medicine group and Integrative Medicine group, respectively, to be conventional western medicine treatment and western medicine on the basis of conventional therapy plus the Kangda Xin treatment; treatment 14 days after the review Plasma NT-proBNP concentrations and echocardiographic indicators. 3 using the SPSS 13.0 statistical software for data analysis. Results: 1.CHF patients with an average concentration of plasma NT-proBNP compared with the normal control group was significantly higher for (1 848.07 ± 721.21) Pg / ml and (268.23 ± 120.60) pg / ml, the difference is very significant (P <0.01). 2 plasma NT-proBNP concentration with NYHA heart function grading was significantly positive related (r = 0.856, (P <0.01)), and LVEF was significantly significant negative correlation (r = -0.785, (P <0.01)), and LVESD was significant with a positive correlation (r = 0.664, P <0.01) and LVEDD was a significant positive correlation (r = 0.636, P <0.01). After treatment, the two groups of patients with plasma NT-proBNP concentrations than before treatment were significantly reduced, the difference was significant (P <0.01); Integrative plasma NT-proBNP concentration after treatment than western medicine group reduced more obvious difference is very significant (P <0.01); After treatment, LVEF significantly improved heart function improved significantly, the difference is very significant (P <0.05). 4 Chinese and Western medicine combined treatment group efficacy superior to western medicine treatment group (92.31% vs 80.0%, P <0.05). Conclusion: Compared with normal physical examination, CHF plasma NT-proBNP concentration was significantly higher, and gradually increased with the heart failure severity and functional status can better reflect the heart; 2 plus yang qi, Blood and Water Chinese medicine \
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