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Analysis on Surveillance of Influenza in Xinjiang from 2004 to 2008

Author: MaZuo
Tutor: ZhengYuJian；LiXinLan
School: Xinjiang Medical University
Course: Public Health
Keywords: Influenza Surveillance Epidemiology
CLC: R181.8
Type: Master's thesis
Year: 2008
Downloads: 204
Quote: 0
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Abstract


Objective To explore the law of influenza activity for the control and prevention of influenza. Methods Monitor influenza epidemiologically, etiologically, serologically by influenza surveillance system. Results After epidemiological surveillance from2004 to 2008, it was found that 4.33%～7.52% of the total outpatients from 2004～2008 were respiratory infection cases in 4 monitor hospitals in Xinjiang Uygur Autonomous Region by using the surveillance system. According with the popularity in wintertime and springtime of north area, The ILI reached the peak in November and January of the secondary year, There were 23 outbreaks reported during the 4 years, and the missing report rate of outbreaks in 2005～2006 was relevantly high. During the pathogenic surveillance in 2004～2008, 230 strains of influenza viruses were isolated, and the positive rate of the isolated viruses reached the peak in 2005～2006(34.1%), and decreased fiercely in 2006～2007(4.7%). The predominance strain was different in each year. Through the serological surveillance, the positive rates of antibodies against H1N1, H3N2, B (Victoria) and B (Yamagata) in general group were 82.79%, 86.74%, 57.91%, and 55.81% respectively. The positive rates of antibodies in Kashi City was higher than in Yining City, and the positive in the high age groups rate were higher than in the low age groups. Conclusion Through influenza surveillance, it can be predicted accurately that the activity of influenza reached the peak in wintertime and springtime every year. The predominance strain was different in each year, and the outbreaks of predominance strain in springtime would also be popular strain in winter in the same year. Therefore, it can be safely predicted that the popular strain would be the subtype of A1(H1N1).The level of A-type influenza antibodies was high and reached the average level of human population protection, however, the level of B-type influenza antibodies did not reached the average level, so the outbreak of influenza may be possible. According to the Xinjiang influenza surveillance, the law of influenza outbreak and the period of validity of vaccine protection, it can be suggested that the reasonable inoculated time was from September to November. Through the research, it can be found that the sample quality could influence the virus isolation rate, so qualified sample was the basis of virus isolation. Likewise, during the ILI surveillance, the scope of outbreaks in 2005 and 2006 was not estimate because of high missing report rates of influenza. The prevention and control work must be strengthened in the future. From 2003, 13 avian influenza (H5N1) outbreaks were reported in Xinjiang with 1 human avian dead case. Whether the avian flu virus would become a pandemic strain in human has become a matter of global concern. Therefore, influenza surveillance in Xinjiang Uygur Autonomous Region is very important.

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CLC: > Medicine, health > Preventive Medicine,Health > Epidemiology and Prevention of Disease > Epidemiology of the basic theory and methods > Outbreak management
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