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A Study of Chinese Gall Compound Recipe Work as Internal Matrix to Repair Fucation Perforation

Author: WangWenLiang
Tutor: TangRongYin;ZhangYing
School: Fourth Military Medical University
Course: Clinical Stomatology
Keywords: Gallnut Baiji Perforation of pulp floor
CLC: R285.5
Type: Master's thesis
Year: 2008
Downloads: 33
Quote: 0
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Abstract


Treatment of perforation of pulp floor is a thorny issue in the clinical, the prognosis often not ideal. Prognostic factors including perforated, perforation size, patch timing, repairing punctures the material properties is one of the most critical factors. The traditional repair materials calcium hydroxide, silver amalgam, etc., directly to the filling for perforation. However, due to the perforation for \Within barrier technology is designed to prevent the repair material into the periodontal tissue material with good biocompatibility and can withstand a certain pressure, and placed under the silver amalgam or glass ionomer repair materials to prevent overfilling. The obvious advantages of this technology compared to traditional restoration techniques, on the one hand hemostasis, isolated exudation; the other hand to provide support for the closed material surface to prevent its super-charge; along with antibacterial anti-inflammatory promote tissue healing role. Sulfate, calcium hydroxyapatite, calcium phosphate, collagen and other materials have been used for the barrier material, but they have their own deficiencies. There is no traditional Chinese medicine as a the inner barrier material reported. The the experimental homemade compound gallnut as internal barrier material, observed antimicrobial activity of the repair material sealing ability and prevent over filling the role, and animal experiments to understand its effect on the treatment of experimental perforations of pulp floor to explore applied to the clinical feasibility. Experiment vitro antibacterial compound gallnut used as a barrier material perforation of pulp floor experimental experiment measuring compound gallnut, through in vitro antibacterial Baiji on periodontal, endodontic infections common bacteria Porphyromonas gingivalis extracellular bacteria, Fusobacterium nucleatum minimum inhibitory concentration (MIC) and sustained inhibitory effect, to evaluate the inhibition. The results the compound gallnut of the two strains was inhibited and has the same MIC no inhibition the Baiji group of the same concentration; observation time, in varying degrees in each experimental group sustained inhibition, which compound sustained antibacterial effects of gallnut group, 48h maximum, 120h is still a certain bactericidal effect; the Baiji group inhibitory effect was significantly lower than the compound gallnut group. Prompted the same concentration of compound gallnut inhibition than Baiji, the main inhibitory role ingredient for gallnut. The experimental the two compound gallnut as the barrier material in the pulp floor perforation microleakage study of this experiment was observed under the microscope by dye penetrant method microleakage of different materials to repair pulp floor perforation. The results showed that all groups have different levels of leakage. Groups leakage values ??in descending order: amalgam group (A), resin (R), the compound gallnut barrier amalgam group (AM), MTA group, compound gallnut barrier resin repair group (RM) . In addition to the rest of the group, no significant differences between the the the amalgam of compound gallnut barrier repair group and resin repair group, the compound gallnut barrier silver amalgam restoration group and MTA group (P gt; 0.05) between the experimental group pairwise comparisons , were statistically significant (P lt; 0.05). Barrier group was significantly lower than the level of leakage no barrier. The compound gallnut for barrier group had no over filling. The prompt Compound gallnut within the barrier material to repair the perforation of pulp floor can reduce microleakage and patching material can effectively prevent overfilling. After the the experimental compound gallnut used as barrier materials of animal experiments to study the experimental perforations of pulp floor through the establishment of the model of the canine furcation perforation repair using different materials, through histological sections, HE staining, observed relatively repair effect. The results showed a degree of inflammation of the after compound gallnut group Ⅲ ~ Ⅳ; degree of inflammation than three months after the month has been reduced predominantly grade Ⅱ ~ Ⅲ and visible material partially absorbed; hard tissue not observed deposition. Ⅲ ~ Ⅳ grade silver amalgam group after one month into the degree of inflammation; degree of inflammation in the three months after the same grade Ⅲ ~ Ⅳ, without significantly reduced the microscope, a large number of lymphocytes. Also no hard tissue deposition. Mainly Ⅱ ~ Ⅲ grade inflammation MTA group after one month, three months after the majority of the inflammation disappeared, have obvious bone deposition. Blank control group: after one month and up to three months inflammation are Ⅲ ~~ Ⅳ. Granulation tissue through perforation long into the medullary cavity. Its filled with inflammatory cells and hyperplasia of capillaries. No hard-tissue deposition. The prompt Compound gallnut as an internal barrier material can be absorbed by the body, and there is a certain anti-inflammatory effects. In summary, the compound gallnut repair the perforation of pulp floor with antimicrobial resistance within the barrier material requirements, closed, absorbent, anti-inflammatory characteristics, therefore, the clinical application should be some feasibility.

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