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Purpose study JieDuTongLuo the tune liver powder on the efficacy of the high fat diet and streptozotocin -induced diabetic rats , provide a scientific basis for the clinical use of drugs . Feeding Wistar rats a high fat diet , fasting 12h, intraperitoneal injection of 1.2% of streptozotocin 30ma/kg, blank group was injected volume of citrate buffer . Modeling rats were randomly divided into model group , metformin , pioglitazone group and JieDuTongLuo tune liver group . Treatment group respectively 0.5g , 5g, 5g / (Kg ) dose oral administration of different drugs , blank group and the model group were given an equal volume of saline . Administered two months after the index detection . Results detoxification Tongluo tune liver the bulk treatment group 12 weeks glucose , glycosylated hemoglobin , serum insulin , serum total cholesterol and triglyceride levels were significantly lower than the model group (P <0.05 or P <0.01 ) , insulin sensitivity index higher than that of the model group (P <0.01). Each indicator there are different degrees of difference (P <0.05 or P < 0.01 ) compared to treatment group . Conclusion detoxification Tongluo Tiaogan scatter can significantly reduce the animal model of fasting blood glucose , glycated hemoglobin , regulate blood lipids , improved insulin sensitivity , and traditional Chinese medicine with further development, development prospects .
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