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The Application of Chitosan Modified Electrode in the Field of Electrochemical-Sensor

Author: MengYi
Tutor: ZhaoChangZhi
School: Qingdao University of Science and Technology
Course: Inorganic Chemistry
Keywords: Chitosan Chemically modified electrode Chiral Recognition Direct electrochemistry Glucose oxidase Horseradish peroxidase
CLC: TP212.2
Type: Master's thesis
Year: 2007
Downloads: 262
Quote: 2
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Abstract


Chitosan is a chitin by deacetylation reaction of an alkaline polymer polysaccharides , both intramolecular pro / hydrophobic groups , there have coordination ability of amino and hydroxyl groups , and its special molecular structure makes chitosan sugar for many ions , organics, and other biological molecules with ion exchange , chelation , adsorption and other effects, have been widely used in food industry, medicine , agriculture and materials science and other fields. In recent years, the use of chitosan and film, biocompatibility, low toxicity , biodegradability , etc., to function as a novel material widely used in chemical sensors and biosensors prepared . This paper studied the modified electrodes and enantiomers of chiral molecular recognition and glucose oxidase, horseradish peroxidase modified electrode electrochemical directly . Paper include the following : Based on the modified electrodes stereoselective chiral molecular recognition. Using chitosan membrane and between enantiomers different stereo effect , by measuring the response current cyclic voltammetry , realized having a cyclic structure of three chiral molecule ( ascorbic acid, epinephrine, tryptophan ) of enantiomer recognition . The optimum pH and chitosan deacetylation degree conditions, three kinds of chiral molecules in the modified electrode enantiomer selectivity coefficient R1 / d , respectively 1.48,1.56,1.67 and use chronocoulometry method the sample of chitosan film tryptophan stereo selectivity to verify the determination of the chiral substance derived enantiomers of formula concentration . Glucose oxidase, horseradish peroxidase in chitosan membrane in direct electrochemical studies . Chitosan as substrate to glucose oxidase (GOD), horseradish peroxidase (HRP) fixed on a glassy carbon electrode, without the use of any nano- materials and electronic media under the conditions of GOD, HRP and electrodes the direct electron transfer (DET). The effects of GOD, HRP in chitosan membrane electrode directly on the electrochemical behavior . Because the molecular mechanism of chitosan and features unique , well maintained the GOD, HRP biocatalytic activity , under certain conditions, the catalytic current and glucose proportional to the concentration of hydrogen peroxide , thereby preparing a non- member of the new electronic media the glucose sensor and hydrogen peroxide sensor .

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CLC: > Industrial Technology > Automation technology,computer technology > Automation technology and equipment > Automation components,parts > Transmitter ( converter),the sensor > Chemical sensors
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