|
This solid acid catalysts Montmorillonite K10 and KSF for four types of organic reactions studied . The full text is in four parts. Part I: K10 montmorillonite catalyst active phenols and cholesterol prepared by the reaction series alkyl , alkylation - Addition , alkylated - Addition - alkylated - product. In this condition has also been active cholesterol etherified phenol , but by controlling the reaction conditions, the generation of selectively alkylated - Addition or etherification product. Under certain conditions the two stereoisomers obtained alkylated - addition products , more than one a small : one is the first in the 3-position of cholesterol active α -position of the phenolic compound with β- alkylated phenols and hydroxyl oxygen to add a double bond in the 5,6 position of cholesterol to form alkylated - addition products ; other is to be coupled into the α- alkylated product . We isolated and purified by alkylation - adduct intermediate alkylation product , using this intermediate in the reaction under the same conditions to obtain the alkylated - addition products in order to verify the reaction mechanism . The new structure of the compound through hydrogen NMR, 13C NMR , hydrocarbon correlation spectroscopy , IR and MS spectra to determine. Part II : In the montmorillonite KSF or K-10 catalyst, catechol and pyrogallol indeed with the corresponding condensation reaction of aldehydes and ketones , synthesized a series of 2 - Substituted and 2,2 - disubstituted benzo -1,3 - dioxolane . 2.6 to 15 hours the reaction completed , to obtain a good yield. The large steric hindrance of the ketone , diaryl ketones and α, β- unsaturated ketone in this condition, the condensation reaction can not occur . Part III: in the solid phase with the adsorbed Fe 3 of montmorillonite or adsorbed FeCl 3 of aluminum oxide catalyst from 2 - naphthol and sulfur Gen 2 - naphthol oxidative coupling reaction , respectively, was obtained 1,1 ' - coupling of 2 - naphthol and 2,2' - dithiobis naphthalene. Part IV: Montmorillonite K-10 catalyst in the hydroxy compound with hexamethyldisilazane alkyl amine to form trimethylsilyl ethers and trimethylsilyl ether cleavage , so as to develop a hydroxyl protecting and de- protection of the new method.
|