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Relationship of Nutrltion in Pregnancy and Astigmatism formation in Twins

Author: ZhouWenZuo
Tutor: ZhangPeiBin
School: Nanjing Medical University
Course: Pediatrics
Keywords: Twins Baby Astigmatism Pregnancy Nutrition
CLC: R778.13
Type: Master's thesis
Year: 2010
Downloads: 13
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Abstract


The purpose of 0-3 years is a critical period of visual development, any impact on visual formation of intrinsic or extrinsic factors can lead to abnormal visual development. Astigmatism is caused by abnormal a common eye fetal eye visual development of infants and young children in intrauterine growth process, the interaction of genetic and environmental, can form different refractive state, so the baby at birth may occur astigmatism. The formation of the astigmatism by the combined effect of genetic and environmental factors, the role of genetic factors in the formation of the astigmatism has been confirmed, the role of environmental factors in the formation of the astigmatism little. A wide range of environmental factors, including maternal-fetal health, maternal-fetal nutritional factors, birth conditions, including nutrient level of astigmatism at home and abroad has not been relevant prospective study. Maternal and child nutritional status during pregnancy and the incidence of astigmatism after birth of twins This paper aims to explore the relationship of nutrition during pregnancy with twins astigmatism. To March 31, 2008 to March 31, 2009, 28 pairs of twins in childbirth in the Jiangsu Provincial People's Hospital, as the research object, which monozygotic twins 11 pairs (5 men and 6 women) and dizygotic tires 17 pairs (8 male and 6 female, three pairs of the opposite sex). Were pregnant in April-June, before delivery extraction mother fasting venous blood and umbilical vein serum nutrient detection in collecting placental umbilical cord stump immediately after delivery, enzyme-linked immunosorbent assay serum 25 - hydroxyvitamin D3, high-performance liquid phase serum vitamin A chromatography, atomic absorption spectrometry determination of serum levels of calcium, iron, magnesium and zinc. 28 pairs of twins born after March, June, September, December, 18 months refraction, astigmatism conditions twins pregnant mother during pregnancy and the twins before birth, after other relevant factors Analysis. The same period, 56 cases were randomly selected single fetus as a control. Results in March after birth of twins, December cylinder ≥ 2D astigmatism detection rate were 53.57%, 43.75%, significantly higher than single birth babies (χ2 = 21.35,18.52, P lt; 0.05). With or without astigmatism family history of twins, astigmatism values ??between the two groups (F = 6.33, P = 0.01) the twins group difference was statistically significant with a single fetus group astigmatism genetic correlation for 58.33%, 57.14%, respectively. Mother of the early response (OR = 1.40,95% CI 1.10-5.13), the mother second trimester bone mineral density (OR = 1.44, 95% CI1.30 ~ 6.19), hemoglobin (OR = 1.69, 95% CI 1.03-2.78), serum magnesium (OR = 1.39,95% CI 1.03-1.89), vitamin A (OR = 1.03,95% CI 1.01-1.06), twins childbirth cord blood vitamin D (OR = 1.02,95% CI 1.00-1.04) and birth weight (OR = 1.02,95% CI 1.00-1.03) and twins astigmatism associated with statistically significant (P lt; 0.05). Conclusions twins astigmatism detection rate was significantly higher than that of single fetus; affect the nutritional status of the mother during pregnancy to twins in the formation of astigmatism, should be targeted throughout the pregnancy on maternal nutritional guidance, in order to reduce the incidence of infant astigmatism

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CLC: > Medicine, health > Ophthalmology > Eye dioptrics > Eye application dioptrics > Astigmatism
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