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Objective: To compare percutaneous cryosurgical ablation and cryosurgical targeting frozen targeted cryoablation combined with 125I seed implantation in the treatment of non-small cell lung cancer imaging value. MATERIALS AND METHODS: cryoablation technology and cryoablation technology seed implantation in our hospital with a total of 42 cases of non-small cell lung cancer, CT-guided imaging data suggest that the tumor size, target synchronization frozen to the piercing unresectable lung tumors in vivo ablation, or the same time to implant 125 - iodine particles, according to the treatment method is divided into Group A (cryosurgical intervention) 22 cases, B group (cryosurgical intervention particles plant into 20 cases), followed by chest CT dynamic changes observed before and after treatment, the lesions were selected preoperative and postoperative 1 week, 1 month, 3 months, 6 months and 12 months time points observed tumor size, density variations and analysis, evaluation of the frozen zone tumor changes, in order to judge the effect of treatment. The statistical software SPSS13.0 for data analysis. Count data using χ2 test, analysis of variance, measurement data using the x ± s and P lt; 0.05 significant difference. Results: A B two groups of patients, in all cases the average hockey coverage gt; 80% to 81% of cases Hockey coverage gt; 80% between the two groups hockey coverage difference was not statistically significant. According to tumor size divided into 3 ~ 5cm larger than 5cm in two types of tumors less than 5cm in diameter, more than 90% of the significant efficiency and better short-term efficacy diameter; the tumor diameter gt; 5cm tumor, significant efficiency 70%. Argon-helium closely related to the local effects of targeted therapies with tumor size, the lesion diameter the size of the local therapeutic effect contrast significant differences (P lt; 0.00). Argon-helium target instantly freeze-thaw effect the treatment of lung cancer depends on the size of the tumor, the tumor the greater, the more residual. 6 months to 1 year follow-up after cryoablation ablation therapy, CT value lower than the preoperative more than 30HU accounted 66%, in accordance with the evaluation criteria of solid tumors after 1 week, 1, 3, 6, and 12 months later CT showed one week after the tumor volume increased 100% response rate (RR = CR PR) were 63.6% and 65%; 72.7% and 75%; 54.6% and 85% at 1, 3, 6, 12 months; 59.1% and 80%. Conclusion: The percutaneous cryosurgical freezing effective in the treatment of unresectable lung tumors, seed implantation combined with radiotherapy is effective in the treatment of residual tumor, to further improve the efficiency, accurate positioning of CT scan imaging, easy to operate, safe and reliable and track review and clear images, play an important role in the interventional treatment and evaluation of clinical efficacy and prognostic judgment.
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