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Objective: This study the tachyarrhythmia in rabbits with hyperlipidemia as a model to explore Qi Yang Xin , blood given shock Yixin Therapeutic palpitate side of the tachyarrhythmias hyperlipidemia rabbits model of myocardial cell ion channels , and to lay a basis for the work of its further application . Method : a high fat diet combined with intravenous injection of adrenaline copy tachyarrhythmia rabbit model of hyperlipidemia , 28 Rabbits were randomly divided into model control group given the palpitate square treatment group Yixin , Yixin given palpitate square prevention group , amiodarone control group , and the other to take the 7 only for the control group to observe and compare rabbits arrhythmia appear , time, duration , and colorimetric determination of rabbit myocardial tissue Na-K-ATP enzyme activity . RESULTS: Yixin set the palpitate square prevention group , amiodarone control group compared with the model group , tachyarrhythmia time delay , and reduces the duration , the difference was statistically significant ( P lt; 0.05 ) ; model control group and blank compared to the control group , the myocardial tissue Na-K-ATPase activity decreased, the difference was statistically significant ( P lt; 0.05 ) ; Yixin given the palpitate square prevention group , the the amiodarone control group and the model group , the myocardial tissue Na -K-ATPase activity increased , the difference was statistically significant ( P lt; 0.05 ) ; the given the palpitate square control group Yixin Yixin given the palpitate square treatment group , the myocardial tissue Na-K-ATPase activity increased , the difference was statistically significance (P lt; 0.05). Conclusion: Yixin given palpitate can only improve hyperlipidemia tachyarrhythmia rabbit myocardial tissue Na-K-ATPase activity , may be a certain role in the prevention of coronary heart disease tachyarrhythmia .
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