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Objective: investigate the the Guangzhou area children with viral encephalitis (VE) pathogens constitute circumstances and popular features . 2 , to understand the the Guangzhou area colti viruses that cause encephalitis . Methods : 1 , 198 cases of VE patients fluorescent PCR method , virus detection in cerebrospinal fluid of 100 cases of other encephalopathy patients , enzyme-linked immunosorbent assay CSF pathogenic antibody IgM. JE IgM antibody , 65 cases of VE and 50 cases of other encephalopathy the patient colti virus double serum IgG antibodies detected by ELISA method to detect patients with RPHI method . 1.198 copies of cerebrospinal fluid viral and ( or ) antibody-positive , 66 cases , the positive rate of 33.6 %. Wherein of EV 25 cases , HSV1 19 cases , HSV2 1 , CMV 3 cases , IFV 1 , ADV 5 Example , JEV 6 , RSV , EBV 3 cases , the measles virus is not detected . Other encephalopathy patients were negative. Viral encephalitis throughout the year distributed more May to October . EV and JEV viral encephalitis caused by the summer and autumn common younger more common ; herpes virus encephalitis full year distributing obvious seasonal , more older children . 3.65 cases of encephalitis patients paired serum the seven cases colti virus IgG antibodies to four times or more higher positive rate of 10.7% . 50 cases of encephalopathy patients positive rate of 4 % ( 2 / 50 ) . Conclusion 1 , enterovirus , herpes simplex virus is the major pathogen of the Guangzhou area children with viral encephalitis , intestinal virus occurs mainly in summer and autumn , more common in younger children : herpes simplex virus encephalitis full year distributing more common in older children . 2 , Guangzhou there are a virus encephalitis virus infection colti .
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